Rheology Of Topical Pharmaceuticals For New Product Development Or Generic Equivalents

By Morgan Ulrich and Sarah Cotts

Potential pharmaceutical products are highly regulated and must be rigorously tested to ensure the safety, purity, and performance are market ready. In topical medicines, the active ingredient can be present in many forms. The FDA insists that properties such as solubility and particle size are considered as part of the manufacturing process. Rheology is one of the methods to provide information on both the bulk and microstructure of topical treatments. The types of properties measured in rheology include the ‘flow curve’ (viscosity versus shear rate), yield stress and viscoelasticity.

Explore how the Discovery Hybrid Rheometer offers capabilities beyond the traditional viscometer.