The Thermo Scientific™ HyPerforma™ Single-Use Fermentor (S.U.F.) and Thermo Scientific™ HyPerforma™ Enhanced Single-Use Fermentor (eS.U.F.) are designed to provide enhanced functionality, ease of use, and efficiency. The complete HyPerforma S.U.F. or HyPerforma eS.U.F. system consists of a fermentor tank and a Thermo Scientific™ HyPerforma™ S.U.F. BioProcess Container (BPC) or a Thermo Scientific™ HyPerforma™ eS.U.F. BPC, which is available in 30 L and 300 L sizes. The HyPerforma S.U.F. BPC features a 5:1 turndown ratio in Thermo Scientific™ Aegis™ 5-14 and CX5-14 film options. The HyPerforma S.U.F. and HyPerforma eS.U.F. maintain traditional stirred-tank fermentation design principles, including specific height-todiameter ratios (3:1) and a top-driven impeller location that delivers optimum cell viability, performance, and scalability from process development through production.