Application Note

Streamlining Seed Train Scale-Up Through Utilization Of The Turndown Ratio Of Single-Use Bioreactors


Upstream bioproduction has seen a substantial movement in the industry toward single-use systems. This has been driven primarily by the need to reduce contamination risk and cleaning requirements when compared to stainless steel systems, and to allow for faster changeover of equipment between batches. At the same time, bioprocessing manufacturing processes have matured significantly, and intensification of cell culture processes has pushed the limits of these legacy single-use systems.

Learn about the a next-generation bioreactor for the biopharmaceutical industry launched by Thermo Fisher Scientific with this evaluation of the performance of the DynaDrive S.U.B.s across all scales from 50 to 5,000 L in a fed-batch process using CHO cells.

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