Study Of Media Evaporation In Nunc Cell Factory Systems

Nunc Cell Factory systems have been used for anchoragedependent cel culture in the fields of vaccines, cell therapy, and gene therapy. Osmolality and pH are important physicochemical parameters, that can be affected by evaporation. To assess the evaporation of media, a series of experiments was conducted to calculate the weight lost in a Nunc Cell Factory system with venting caps and another system with sealing caps.