The Challenges Of Terminal Sterilization

By Thomas Ofenboeck and Christian Dallner, Syntegon

Sterilization is one of the most crucial processes in the entire drug manufacturing process, as it is responsible for ensuring patient safety. some containers risk to burst, warp or lose stability during terminal sterilization. These potential negative impacts on the product’s final validation entail long delays and additional costs for manufacturers. Hence it is vital to find the appropriate terminal sterilization method for all drugs and containers. Learn more about the differing parameters, depending on both medication and primary packaging, that pose various challenges to pharmaceutical manufacturers.