White Paper

The Role Of pH And Residue In Pharmaceutical Cleaning

Source: Alconox Inc.
Washing vials GettyImages-498492058

By Malcolm McLaughlin, Alconox

A great deal is known about how pH affects aqueous critical cleaning. Typically, alkaline cleaners are used on oily residues and acidic cleaners are used on inorganic residues. Robust fully formulated cleaners that contain wetting agents, emulsifiers, dispersants, chelating agents and anti-redeposition agents will give the broadest and most robust residue removal. Different types of residues are best cleaned by either an alkaline or acidic cleaner. The following table outlines the types of chemical structures found in pharmaceutical residues that are best cleaned by either acid or base. Some residues can be cleaned by either, but will tend to lean toward one type for most efficient results.


Get unlimited access to:

Trend and Thought Leadership Articles
Case Studies & White Papers
Extensive Product Database
Members-Only Premium Content
Welcome Back! Please Log In to Continue. X

Enter your credentials below to log in. Not yet a member of Pharmaceutical Online? Subscribe today.

Subscribe to Pharmaceutical Online X

Please enter your email address and create a password to access the full content, Or log in to your account to continue.


Subscribe to Pharmaceutical Online