The Significant Need For Flexible Aseptic Filling And Isolation Systems In Pharma

By Giel Van Veen

Technological developments in the pharmaceutical industry have advanced rapidly over the last decades. One field of particular interest has been aseptic and sterile primary packaging. Primary packaging of pharmaceutical products often involves filling containers (including vials, syringes and bottles) with powders and/ or liquid solutions. Manufacturing staff, equipment and premises are all subject to stringent quality controls – and for good reason: patient safety.

In order to ensure the safety and quality of pharmaceutical products, every manufacturer in the pharmaceutical industry is compelled to adhere to the Good Manufacturing Practice (GMP) guidelines. Recently, a complete draft revisionI of Annex 1 (Manufacture of Sterile Medicinal Products) of the GMP has been released. This document intends to provide information on the latest status, trends and technologies in parenteral filling equipment.