Article | April 20, 2023

What Is Isothermal Titration Calorimetry (ITC)?

By Neil Demarse and Morgan Ulrich

Isothermal Titration Calorimetry (ITC) is an experimental method used to measure the amount of heat released or consumed during a bimolecular chemical reaction. A single ITC experiment can be used to calculate binding affinity, binding specificity, and the ratio of the binding (stoichiometry). Explore ITC instruments and how ITC is applied and improving vaccine therapy research.

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