Capsule Production White Papers & Case Studies

  1. 5 Steps To Increase Energy-Efficient Mixing

    Mixer testing simulation trials are needed to confirm the suitability of a specific mixing strategy. This white paper explores five ways to increase energy efficiency in new and existing mixing processes.

  2. Efficiencies In Powder Dispersion For Manufacturers

    Uniformly dispersing powders into a liquid batch in a practical amount of time is a common problem for F&B manufacturers. This white paper explores five tips for dispersing powders more efficiently.

  3. Development Of Biopharmaceuticals Requiring Lyophilized Formulations

    Development of a drug formulation and lyophilization (freeze drying) process begins with laboratory experiments followed by scale up to larger lyophilizers. 

  4. Modular Facility Design: A Cost-Effective Option In The Post-Blockbuster Drug Era

    The pharmaceutical industry has undergone a sea of change in recent years as manufacturers have adapted to the end of the era of large-volume production of mass-market blockbuster drugs. With firms now focusing in on subpopulations of patients, there is a need for lean, adaptable facilities that can switch quickly between multiple products in multiple formats. Modular facilities can meet this need. While not a panacea, for the right project characteristics, ‘Modularity in Design’ can deliver significant and quantifiable long-term value.

  5. Fundamentals Of Spray-Dried Dispersion Technology

    A common problem statement in the pharmaceutical industry is low oral bioavailability of drug candidates with poor aqueous solubility.

  6. Fluid Bed System Triples Batch Sizes for Laboratorios Normon while Reducing Costs

    With the aim of reducing costs, Normon planned to significantly increase its batch sizes for certain products. The manufacturer needed to pay close attention to the high quality and safety standards and economic aspects, as well as flexible production sizes and times.

  7. Medication Errors -- A Threat To Patient Safety: Mitigating Errors With Tablet Appearance

    Medical prescription drug errors by doctors, pharmacists and patients account for 1.5 million incidences of sickness, injuries or deaths in the U.S. each year. By Jay Anbil and Steve Yoder 

  8. Film Coating For Pediatric Oral Solid Dosage Forms

    From a recent survey conducted within the pharmaceutical industry, by Colorcon, it was confirmed that oral solid dosage forms are a preferred choice for formulation of pediatric medicines.

  9. Accelerating Lipid-Based Drug Formulation

    Formulation scientistsmust develop and validat robust systems that address the challenges posed by increasingly complex drug candidates, in ever shortening time frames.

  10. When Capsules Fall Apart, Who Is To Blame?

    Capsule integrity is a given for established manufacturers with impeccable reputations.  Consumers, however, know from experience that not all capsules are made equal.  Some can be difficult to extract from the blister pack.  Others may have gel caps with cracks or, even worse, ruptures that allow the ingredients to spill out.  Is this a manufacturing problem?  Or has R&D neglected to implement a fool proof test methodology for evaluating capsule stability?  Compression and tension testing offer a technical approach with quantifiable results that can be used to assess capsule performance.