Featured Articles

11. Genderless Single-Use Connectors Make For Easier Systems Design, Flexible Process Flow

    Colder’s John Boehm tells Pharmaceutical Online’s Lori Clapper about the evolutions of single-use technologies and the trend towards downstream processes.  He discusses how, in the growing demand and adoption of single-use technologies, the unit operations are incorporating more single-use systems whether its bag systems and tubing assemblies. However, as they get larger and larger, it is difficult to sterilize those in one large piece. So they are typically broken down into individual units. The key to having a completely single-use system, or even a hybrid system, is you have got to bring those systems together. Colder has responded to this challenge by creating the AseptiQuik G connector (G for “genderless”) to create process flexibility for the end user.

12. How To Protect High-Value Media With Single-Use Connectors

    When dealing with high-value products in your downstream processes, the last thing you want is for your media to end up on the plant floor.

13. The Benefits Of Converting To Single-Use For Bioprocessing Systems

    Single-use is an inexpensive and flexible way to bring that product into the process, yet the value of that product was low enough that they were willing to take a risk on a new technology.

14. Single-Use Connections Advance Aseptic Processing

    John Boehm discusses how single-use connections advance aseptic processing and create increased process flexibility and reliability while reducing costs.

15. Connection Technology Advances Closed System Processing

    The global demand for new biologics and vaccines, combined with the growing emergence of biosimiliars, is challenging drugmakers to re-evaluate their processes and seek ways to make them more flexible, reliable, and cost-effective. By John Boehm, Colder Products Company

16. Combination Sterile Connections For Single-Use Applications

    Gain insight into why combination connections are used in single-use bioprocessing and guidance on how single-use systems can be designed to integrate the combination connectors.

17. Genderless Sterile Connectors Offer Flexibility And Faster Changeovers

    Genderless sterile connectors — with their ability to interconnect with each other without male/female limitations — can enhance the flexibility of single-use systems in a range of bioprocessing applications.

18. The Benefits Of Genderless Sterile Connectors For Single-Use Applications

    Genderless connections are those in which the connector halves are identical in design, thus eliminating the need for different male and female halves to make the connection.

19. The Value of Closing Your Process

    For R&D and PD applications, closed, single-use systems can protect against both biological and cross-contamination, saving valuable research time and money.

20. Implementing Global Best Practices For Single-Use Systems

    Single-use technology has only been used at manufacturing scale for about 10 years. Relative to other technologies, single-use systems are new and experience can be limited.