Containment & Isolation White Papers & Case Studies

31. Advantages Of Gamma Irradiation For Effective Sterilization Methods

    Many sterilization methods are available for pharmaceuticals, healthcare devices, and labware, including steam, sterile-filtration, ethylene oxide, vapor-phase hydrogen peroxide, electron-beam irradiation, and gamma irradiation. Each technique needs to be evaluated before use based on various criteria. Most importantly, one must consider how the technique will affect the final product characteristics and performance. By Betty Howard, Radiation TechTeam Manager, STERIS Isomedix Services

32. Strategies For Gamma Sterilization Of Pharmaceuticals

    A crucial step in pharmaceutical production is sterilization. There are many sterilization methods to choose from, such as steam, sterile filtration, ethylene oxide gas (EtO), electron beam (E-beam), and gamma radiation. Each technique has aspects that make it suitable or unsuitable for the sterilization of a particular product. By Ruth Garcia, Betty Howard, Rose LaRue, Glenn Parton, and John Walker, Steris Isomedix Services

33. Ultraviolet Disinfection: Crucial Link In The Sterilization Chain

    Many manufacturers face the challenge of maintaining sterile products and processes. In most cases, there’s no one-size-fits-all solution. By Alex Verayo

34. How To Reduce Cleanroom Costs

    As cleanrooms grow in size and sophistication, energy demands go up significantly. Even worse, 24/7/365 operation puts substantial particulate loads on filters, increasing maintenance costs and possibly causing unpredictable – and expensive – cleanroom maintenance shutdowns. By Alex Verayo

35. Designing An Effective Pharmaceutical Containment Blending System

    The same pharmaceutical Intermediate Bulk Container (IBC) that is used for shipping and storage can also be used for blending. 

36. Surrogate Testing Of A Downflow Booth Complete With Integrated Tray Dryer

    Walker Barrier Systems was tasked with providing two downflow booths, each with integrated tray dryer (client provision) mounted in the side wall. The booth was to be used for filling trays with wet cake, as well as the dispensing of dried product from the trays into drums using a custom designed “tray dispensing hopper”.

37. Container Closure Integrity Testing For Prefilled Syringes

    In this article, we highlight our current thinking in an attempt to devise a systematic approach for CCI testing method selection, development, and validation.

38. Improve Efficiency In Bio-Contamination Control And Risk Mitigation

    There is a need to improve the efficiency in the pharmaceutical industry to meet new challenges of globalisation, competitiveness and the increasing diversity of products. By James Drinkwater

39. Biological Contamination Management In Aseptic Environments: Requirements And Expectations

    Bio-contamination found in critical zones within processing environments can affect the whole process and sterility of the final products, potentially putting patients at risk. This can lead to significant financial costs and impact operational resources. By James Drinkwater

40. 5 Questions To Ask Yourself Before Purchasing A Containment System

    If you are considering purchasing a containment system, here are five questions to answer that will help you prepare before contacting or working with a containment system vendor.