Contract Manufacturing Featured Articles

  1. Criteria For Effective Bioprocess Scale-Up 3/25/2026

    Discover four essential bioprocess scale-up criteria and how each balances hydrodynamics, shear, and mass transfer across manufacturing scales.

  2. When To Consider Material And Personnel Airlocks For Downflow Booths 3/20/2026

    Strategic use of airlocks in downflow booth design enhances pressure stability and containment. A risk-based approach ensures facility integration meets rigorous safety and compliance standards.

  3. Continuous Flow — An Emerging Alternative 3/17/2026

    Gain insights on transitioning from batch to continuous flow processes, the benefits of continuous flow chemistry, and ensuring regulatory compliance with Quality by Design (QbD) principles.

  4. Small Molecule API Production: Unveiling The Impact Of Fermentation 3/17/2026

    Technological developments have led to growth in the suitability of fermentation for a myriad of applications. Explore the impact of the evolution of synthetic biology and supporting technologies on modern fermentation practice.

  5. Accelerated API Manufacturing: Combining All Process Development Stages 3/17/2026

    During early-stage development, utilize the key considerations outlined in this paper to avoid common pitfalls and expedite the transition from molecule to market.

  6. Patented Process For Intermediates Useful For Etrasimod Arginine 3/13/2026

    Explore how rethinking the synthetic strategy for Etrasimod can overcome the limitations of legacy routes, enabling more efficient chirality control, improved scalability, and more practical industrial API production.

  7. New MIT Consortium Links Innovation With Real-World Biomanufacturing 3/6/2026

    In one area, the Initiative for New Manufacturing is exploring whether microfactories, championed by the EV industry, can help biopharma iterate facility design faster.

  8. The Paradigm Shift: Why Process Intensification Is Gaining Traction 3/4/2026

    While fed-batch processes have long been the biomanufacturing standard, intensified processes are offering the opportunity to increase productivity, reduce COGs, and achieve sustainability targets.

  9. Comparing Process Development Approaches For Recombinant Proteins 2/26/2026

    Explore how adding a traceless tag enables streamlined affinity purification for recombinant proteins, and how this approach compares with a conventional process in development time, recovery, and purity.

  10. Building the Next Generation of TIDES Manufacturing Excellence 2/12/2026

    Rising demand for complex TIDES therapies is shifting manufacturing expectations, driving adoption of continuous processing, digital tools, stronger supply strategies, and greener, scalable synthesis.