Containment & Isolation White Papers & Case Studies

31. Variability In Sterility Test Processes And The Benefits Of Modular Workstations

    This paper reviews some of the current operational practices that incorporate sterility testing and provides an insight into the role of hydrogen peroxide vapor bio-decontamination and continuous particle monitoring. By James Drinkwater, Bioquell UK Process & Compliance Director

32. Designing An Effective Pharmaceutical Containment Blending System

    The same pharmaceutical Intermediate Bulk Container (IBC) that is used for shipping and storage can also be used for blending. 

33. Surrogate Testing Of A Downflow Booth Complete With Integrated Tray Dryer

    Walker Barrier Systems was tasked with providing two downflow booths, each with integrated tray dryer (client provision) mounted in the side wall. The booth was to be used for filling trays with wet cake, as well as the dispensing of dried product from the trays into drums using a custom designed “tray dispensing hopper”.

34. Improve Efficiency In Bio-Contamination Control And Risk Mitigation

    There is a need to improve the efficiency in the pharmaceutical industry to meet new challenges of globalisation, competitiveness and the increasing diversity of products. By James Drinkwater

35. Biological Contamination Management In Aseptic Environments: Requirements And Expectations

    Bio-contamination found in critical zones within processing environments can affect the whole process and sterility of the final products, potentially putting patients at risk. This can lead to significant financial costs and impact operational resources. By James Drinkwater

36. 5 Questions To Ask Yourself Before Purchasing A Containment System

    If you are considering purchasing a containment system, here are five questions to answer that will help you prepare before contacting or working with a containment system vendor.

37. Benefits And Risks Of (UV) Ultraviolet Radiation

    Soon after the discovery of microorganisms, biologists began to observe that many varieties of these creatures were able to be incapacitated by exposure to sunlight. Following the discovery of the ultraviolet bandwidth in 1801, scientists attributed the sun’s lethal effect to this invisible energy. Facilitated by the findings of a large body of experimental evidence collected in the decades following these initial hypotheses, contemporary scientists have determined that nearly all bacterial activity can be eradicated or at least attenuated by some wavelength of ultraviolet energy.

38. Continued Process Verification Methods In Cleaning Validation

    An increasing interest in continued process verification has led to the spread of on-line assay methods in cleaning processes. This paper deals with two different on-line applications: conductivity sampling and the Total Organic Carbon analysis for washing machines.

39. Innovative Valve Interfaces Ensure Customized Productivity In B. Braun LIFE Nutrition Plant

    B. Braun Melsungen AG is one of the leading companies in the international pharmaceutical and medication sector. With an investment of 164 million Euros the company is currently building the LIFE Nutrition plant, one of the world’s most modern production sites for innovative nutrition solutions, at the company headquarters in the North Hessian city of Melsungen. Jens Voigtländer, Editor

40. Guide To Pharmaceutical Isolation Systems

    Isolation and Containment technology provides a safe working environment for manufacturing operators in R&D, testing, and material handling of hazardous and potent materials, such as active pharmaceutical ingredients.