Featured Articles

  1. Automated Bag Thawing System For CAR-T Cell Therapy Manufacturing 1/11/2022

    The performance of the VIA Thaw CB1000 is compared to thawing in a water bath. The VIA Thaw™ dry thawing system shows comparable performance to a water bath with less handling.

  2. Scalable AAV Purification Process For Gene Therapy 11/22/2021

    Processes to produce AAV for gene therapies are in place, but there’s room to optimize purification to achieve high overall yields and efficiently remove empty capsids and other impurities.

  3. Process Development For AAV Vector Production In Suspension Cells 11/19/2021

    Review experiments for the adaptation of the HEK293 suspension cell line for transient transfection and scalable adeno-associated virus (AAV) production.

  4. Shipping Temperatures For Cell Therapies 5/14/2021

    Cryopreserved cells are often stored at a central facility before being shipped to the clinical location. This study explores the required shipping and storage temperatures for cryogenic cold chain delivery of biological samples.

  5. Overcoming Cell Therapy Supply Chain Challenges 5/11/2021

    For the industry to realize the potential of cell and gene therapies (CGTs), we must develop improved solutions that reliably support the control and transport of critical CGT raw materials and products.

  6. Consistency And Compliance: Cell Therapy Automation Software 4/30/2021

    Automation offers new options for flexibility and optimized biologic production, improving safety, quality, and compliance while advancing patient care.

  7. The Science Of Cell Therapy Thawing 4/5/2021

    A summary of the science of thawing following conventional slow freezing methods, the physical and biological implications of key metrics and components, and key studies from scientific literature.

  8. Cell Therapy Scale-Up Strategies For Commercial Success 9/30/2020

    This article discusses options for cell therapy process development and validation that minimize risks through quality control (QC), optimization, scaling, closing, automation, and assay development.

  9. Robust Process Development For cGMP Manufacturing Of Cell Therapies 9/24/2020

    By leveraging early decisions around process development, quality assurance, and quality control strategies, you can set yourself up for a successful cGMP manufacturing workflow. 

  10. Platform Cell And Gene Therapy Media Development 9/9/2020

    This article highlights a case study on the removal of serum from the expansion step of an autologous cell therapy in a cost-effective manner without affecting cell performance.