Liquid Dose Featured Articles

1. Managing Extractables And Leachables In HPAPI Manufacturing 7/10/2025

   These contaminants can compromise the quality, stability, and safety of a drug product, and regulatory bodies mandate assessment to protect patients.

2. Scaling Up Manufacturing? Here's Why You Need A CMC Specialist 6/16/2025

   CMC experts (whether in-house or outsourced) fill a vital role during the transition from small-scale production to larger operations for maintaining quality, consistency, and compliance.

3. Aseptic Extrusion: Preventing Contamination And Ensuring Product Sterility 6/12/2025

   Pharmaceutical extrusion is a key manufacturing process. Discover the critical process considerations and custom engineering required to handle temperature-sensitive and high-viscosity pharmaceutical materials.

4. Cleaning Process Capability: Understanding Populations, Samples, And Sample Size Requirements 6/6/2025

   This article examines the role of sample sizes in the determination of cleaning process capability or process performance in the manufacture of drugs/therapies and medical devices.

5. Radiopharmaceuticals: Navigating FDA Guidance And CMC Considerations 6/2/2025

   The unique nature of radiopharmaceuticals necessitates specialized regulatory considerations, particularly for chemistry, manufacturing, and controls (CMC).

6. Responding To Fill-Finish And Automation Scale-Up Challenges 5/21/2025

   Behind every life-saving cell therapy is a complex manufacturing journey. Examine the critical role of automation in overcoming production challenges and ensuring quality.

7. Small Molecule Pharma Companies Are Employing These Advanced Technologies To Get Ahead 5/19/2025

   Small molecule drug companies are employing these concrete innovations, including several associated with Pharma 4.0, all boosting quality and efficiency.

8. A Road Map For PAT Monitoring And Control 5/8/2025

   Process analytic technology monitoring and control is rapidly progressing. BioPhorum shares new best practices on how to move from concept through life cycle management and/or regulatory approval of the PAT application.

9. Accelerating The Industrialization Of CGT Manufacturing 5/1/2025

   Patent expiry of original product enables 3P innovation to design enhanced equivalent DPI filling system for developers and CMOs.

10. Biofluorescent Particle Counters Are Gaining Momentum 4/28/2025

    The 2025 BioPhorum report highlights challenges and trends in drug filling operations and how they are advancing towards biofluorescent particle counters. Discover an approach that aligns with industry needs.