Liquid Dose Featured Articles

1. Planning For Scale Up: Building For Long Term Flexibility 8/31/2026

   Decisions made during clinical manufacturing have lasting consequences at commercial scale. This article examines how fill/finish equipment choices shape long-term flexibility, throughput, and operational continuity.

2. Protecting Your Drug Product: Integrating Engineering And Quality 8/31/2026

   Engineering decisions in fill/finish directly shape product quality and sterility assurance. This article examines how inert gas purging, plunger placement, dosing verification, and barrier systems interact across line design.

3. Expanding Subcutaneous Design Brick By Brick 8/14/2026

   Biologics are growing more complex. But what if the syringe itself could unlock new possibilities? Discover the technology “bricks” quietly reshaping subcutaneous drug delivery.

4. The Clear Solution: Navigating Contamination Control For Ophthalmic Injectables 8/12/2026

   As the intravitreal therapy market grows and applicable regulations evolve, continued compliance demands technological savvy and rigorous contamination control.

5. MIDBA: A New Regulatory Approach To Clinical Device Bridging 8/12/2026

   When devices evolve, evidence expectations can shift. Explore a risk-based clinical bridging approach to support regulatory decisions.

6. July Update — U.S. Generic Drug Tariffs: Implications For Pharma And Outsourcing 8/7/2026

   Mathini Ilancheran updates us on how delayed U.S. tariffs on generic drug imports could reshape supply, sourcing, and trial planning.

7. Why Spray Drying Is Gaining Attention 7/20/2026

   Facing patent cliffs, pharma companies can leverage spray drying to reformulate complex biologics, enabling non-invasive delivery, boosting patient convenience, and securing new patents.

8. Rethinking Fill-Finish To Reduce API Loss In Early Development 6/15/2026

   Early-stage drug programs can preserve constrained API supplies by replacing large-scale manufacturing defaults with deliberate, right-sized fill-finish designs that minimize avoidable process waste.

9. The Future Of Continuous Is Integrated Manufacturing: The 4 Misconceptions About A Lean Process 6/2/2026

   Pharmaceutical continuous manufacturing is an enabler of better manufacturing, but only when implemented with intention.

10. Drug Substance To Fill-Finish Handoff: What Sponsors Need To Know 5/14/2026

    Effective drug substance handoff to fill-finish manufacturing depends on early collaboration, clear communication, and proactive planning to reduce risks, ensure quality, and maintain timelines.