Insights On Liquid Dose Manufacturing

  1. Vial Breakage During Lyophilization: Root Causes And Mitigation 10/16/2024

    Learn how controlling freezing rates, using specialized vials, and employing optimized stoppering techniques can reduce the risk of vial breakage during lyophilization and ensure high product quality.

  2. Importance Of Assessing Mannitol Crystallinity In Lyophilized Drug Products 10/16/2024

    Drug product stability may be seriously compromised if mannitol completes crystallization during storage rather than during the freezing or annealing step in the lyophilization process.

  3. Maintaining Cell Viability During The Cryovial Filling Process 4/21/2025

    Maintaining cell viability during cryovial filling is a critical challenge in cell therapy manufacturing. This presentation introduces cryoFIL®, a cutting-edge automated cryovial filling platform designed to deliver high-precision, aseptic, and scalable solutions for cryovial filling.

  4. A New Approach To Isolator Decontamination 4/8/2024

    How can you address the decontamination challenges associated with isolated fill-finish operations? New innovations are being implemented to ensure superior sporicidal reduction and operational safety.

  5. Vial Fogging: Practical Considerations For Vial Selection 10/16/2024

    Vial fogging is a common phenomenon observed in lyophilized biologic drug products. This document presents two case studies that explore critical factors contributing to vial fogging and inform vial selection decisions.

  6. 5 Common Bowie-Dick Test Failures And How To Prevent Them 11/26/2025

    Bowie-Dick test failures indicate serious sterilization issues. Learn the five most common causes and proven strategies to prevent downtime, compliance risks, and compromised product integrity.

  7. Sterility Method Development And Suitability Testing 6/4/2024

    Does each formulation and product type require method development? Explore a matrix approach to method development and suitability testing for the compounding industry.

  8. How Do We Reduce Your Environmental Cost Of Ownership (ECO)? 12/4/2025

    By rethinking cleanroom requirements and reducing resource-heavy sterilization steps, manufacturers can significantly lower their Environmental Cost of Ownership and futureproof their operations.

  9. Jaw Crimping vs. Rotary Crimping: Enhancing Aseptic Assurance 6/12/2025

    Beyond a simple mechanical step, crimping is a critical control point. We examine how advanced rotary technology provides superior seal quality, particulate control, and data-driven compliance assurance.

  10. Accelerating Sterile Injectable Innovation Through Strategic Outsourcing 9/21/2025

    Sterile injectables are vital for modern medicine. Learn how outsourcing manufacturing to a CDMO can accelerate development and commercialization.