Secondary Packaging White Papers & Case Studies

  1. Meeting Technical Challenges In Desiccant Dispensing

    Christopher Garrod knew he would need a desiccant in his sample bottles of Vimovo, but after speaking with his R&D team, Garrod, a senior engineer on the Packaging Process Execution Team for AstraZeneca, immediately realized it would present a unique challenge. Vimovo, a fixed-dose combination of enteric-coated naproxen and immediate release esomeprazole, is a highly moisture sensitive drug. The atmospheric exposure limits for the desiccant were a lot tighter than any product they had packaged before, presenting Garrod with his first challenge

  2. Beyond Sachets: Customized Sorbent Solutions For Increased Packaging Flexibility

    As the healthcare market continues to grow and evolve, sorbent (desiccant, oxygen absorber, hydrocarbon adsorbent) manufacturers are faced with developing new sorbent formats that will allow placement flexibility while continuing to positively impact the drug or device stability profile. By Adrian Possumato, Multisorb Technologies

  3. Challenges In Choosing The Right Sorbent

    Maintaining drug stability, quality, shelf life, safety, and efficacy is often achieved by using a sorbent to manage moisture, remove oxygen, or eliminate volatiles in the drug or device packaging headspace. With so much at stake, sorbent insertion is a critical step in the pharmaceutical packaging process.  Unfortunately for manufacturers, automated insertion can create challenges on the packaging line when not properly implemented by a reputable supplier that can offer technical expertise and customized solutions.  By Adrian Possumato, Vice President, Healthcare Packaging

  4. Scientific Standards For Ambient Temperature Profile Development

    Storing and shipping highly temperature-sensitive drug products requires sophisticated packaging to ensure that the product remains safe and viable — from the manufacturing plant to the end user. By: Kenneth Maltas, Vice President of Engineering Auston Matta,  Engineering Team Lead R&D Kevin O’Donnell,  Technical Director D’Arcy Ryan, Director of Marketing

  5. Dangerous Goods Classification Confusion: UN 3373 Biological Substance, Category B

    In the previous blog post “Infectious Biologicals Category A and B - Classification Guidelines,” I provided definitions of Infectious Biologicals Category A and B and some basic guidelines on how to classify your shipments. These definitions are clear and helpful when you know that your shipment contains pathogens. In that case, it is either on the list for Category A, or if it is not, then it is classified as Category B. By Michael Gotz

  6. Protecting Pharmaceuticals From Degradation

    Pharmaceuticals are subject to a variety of degradation pathways that compromise drug safety and shelf-life. By far the greatest degradation is caused by hydrolysis and oxidation. However, other mechanisms include racemization, photodegradation, elimination, and complexation. By Adrian Possumato