Thermo Fisher Bioproduction Insights

  1. Resolving 5 Challenges Of Novel mAb Purification 3/7/2025

    Thermo Fisher’s CaptureSelect™ and POROS™ resins address purification challenges in novel monoclonal antibodies (mAbs), ensuring high yield, purity, and scalability when traditional Protein A chromatography falls short.

  2. Scale-Up Approaches For Culturing Adherent Cells 3/5/2025

    For successful scale-up, see how optimizing process parameters such as attachment methods, gassing, and agitation can help reduce cell environmental stress, ultimately improving productivity.

  3. Comparison Of Single-Use And Steel Fermentors For Malaria Vaccine Production 3/5/2025

    Support the advancement of malaria vaccine development by leveraging innovative bioprocessing solutions to enable efficient, scalable, and accessible vaccine production worldwide.

  4. Comparative Analysis Of Tubing Retention Devices 3/5/2025

    Single-use tech advances demand better tubing connection methods. Discover an innovative retention device that overcomes issues of traditional ties by delivering consistent, 360° secure connections.

  5. Intuitive Bioprocess Scale-Up From Bench Scale To Pilot Scale 3/5/2025

    This study explores scaling a high-demand fed-batch process from bench to pilot scale, highlighting control parameter differences at 50L and 500L while maintaining consistent growth and product titers.

  6. The Importance Of Quality In Raw Material Selection 1/16/2025

    Learn how to select high-quality raw materials for cell-based manufacturing in this exploration of the criticality of raw materials, from preclinical development to commercialization. 

  7. Viewing HEK293 Transient Transfection Through A Wider Lens 12/11/2024

    HEK293 transient transfection is a leading platform for gene therapies. However, manufacturing challenges remain, particularly in scaling up production.

  8. Enhanced mAb Production With High-Intensity Perfusion CHO Medium 11/27/2024

    Reach new heights in mAb production with a high-intensity perfusion CHO medium designed to support consistently high product yield and quality in continuous perfusion cultures using CHO-K1 cells.

  9. The Value Of Peptones For Enhancing Biopharmaceutical Productivity 11/18/2024

    Peptones, versatile media additives derived from various sources, offer numerous benefits for biopharmaceutical production.

  10. Difco TC Yeastolate Ultra-Filtered (TCY UF) In Scale-Up Optimization 10/30/2024

    Explore how Difco™ TC Yeastolate ultra-filtered (TCY UF) enabled over 100% improvement in titer for CHO cell culture through feed optimization and bioreactor scalability in a real-world application.