In tablet manufacturing, the traditional use of a batch-based wet granulation process presents several issues. An alternative to this is dry granulation by roller compaction. However, to appreciate how roller compaction can benefit manufacturing capacity and efficiency, it is important to first understand the functionality and capability of this technology.
The enhanced precision used in 3D printing can drive efficiencies in early drug development by allowing more flexibility with dosage size and strengths, leading to a more effective use of costly resources.
To address the limitations of oral solid dose forms while also keeping pace with advances in patient treatment, pharmaceutical manufacturers must be willing to consider alternative approaches to developing and manufacturing OSD drugs.
3D printing allows drug companies to not only boost efficacy and adherence but also contribute to their brand longevity by expanding and capturing market share with other dosage form options.
Adults and children alike often struggle with compliance and acceptance of medication regimens due to the sizes and shape of prescribed tablets. One pharmaceutical manufacturer sought to create a convenient, easy-to-swallow dosage form by taking an alternative approach: three-dimensional printing (3DP). This white paper outlines their approach to creating an FDA validated manufacturing process for rapidly disintegrating dosage forms.
Mixer testing simulation trials are needed to confirm the suitability of a specific mixing strategy. This white paper explores five ways to increase energy efficiency in new and existing mixing processes.
Uniformly dispersing powders into a liquid batch in a practical amount of time is a common problem for F&B manufacturers. This white paper explores five tips for dispersing powders more efficiently.
The JetVent system allows for easy and confident handling of expensive and dangerous powders.
Fast Powder Mixing And Complete Protection Of Powder Properties
The efficient mixing of media and buffer powders into liquids is a crucial step in profitable pharmaceutical and biopharmaceutical manufacturing.
In the pharmaceutical industry, granulation is used to create bonds between particles as part of the oral solid dosage manufacturing process.
Milling is a common operation throughout the pharmaceutical manufacturing process. Sizing of powders is a dusty operation and with more potent powders being processed, the need for containing this operation becomes even more critical from safety and cross contamination avoidance purposes.
Tablet coating is a common operation throughout the pharmaceutical manufacturing industry. ILC Dover supplies a family of products that support contained Tablet Coating operation.
Tablet compression is a common operation throughout the pharmaceutical manufacturing industry. ILC Dover supplies a family of products that support contained Tablet Compression operations.
Krämer dedusters ensure a smooth operation daily at the sites of hundreds of pharmaceutical companies, ranging from multinationals to small local manufacturers of tablets and capsules. Our customers appreciate the quality and reliability of our equipment.
The Coperion K-Tron PH line of pharmaceutical design loss-in-weight vibratory tray feeders combine high accuracy with a configuration which is ideal for materials which may not be suitable in twin screw feeders, such as dfficult flowing API‘s. The gentle vibratory feeding principle allows for low rate feeding without build up which can occur on screws and screw tubes. Coperion K-Tron’s patented load cells and KCM controller ensure high accuracy feeding while the easy clean design of the vibratory tray ensure quick and easy product changeover. Specialty control algorithms permit the vibration method of feeding, without interrupting the loss in weight signal.
