In tablet manufacturing, the traditional use of a batch-based wet granulation process presents several issues. An alternative to this is dry granulation by roller compaction. However, to appreciate how roller compaction can benefit manufacturing capacity and efficiency, it is important to first understand the functionality and capability of this technology.
Aprecia Pharmaceuticals had the goal of accommodating formulation designs that could deliver higher drug loads with taste masking or a modified release profile as required.
Mixer testing simulation trials are needed to confirm the suitability of a specific mixing strategy. This white paper explores five ways to increase energy efficiency in new and existing mixing processes.
Uniformly dispersing powders into a liquid batch in a practical amount of time is a common problem for F&B manufacturers. This white paper explores five tips for dispersing powders more efficiently.
This paper provides practical information on the efficient use of specialty mixing equipment for the preparation of low, medium and high viscosity solid-liquid mixtures under low and high shear conditions.
Development of a drug formulation and lyophilization (freeze drying) process begins with laboratory experiments followed by scale up to larger lyophilizers.
ALK-Abelló is a global research-driven pharmaceutical company that focuses on the prevention, diagnosis and treatment of allergies. Before ALK-Abelló partnered with Catalent, all marketed allergen immunotherapies were delivered by injection, resulting in a limited patient population and reduced patient adherence. Catalent worked with the client to apply Zydis Fast Dissolve Technology to their therapy. The overall result was a marked improvement in patient tolerability, preference and compliance.
Natoli Engineering is quickly becoming the leader in R&D tablet presses with this next-generation rotary tablet press. Designed to help solve formulation and scale-up challenges, the NP-RD30 rotary R&D tablet press replicates the design and functionality of a production press. The turret velocity of the NP-RD30 can reach that of production presses, meaning dwell time can be more accurately established during research and development.
Natoli Quick-Release Tablet Tooling allows researchers to test different dwell times during the tablet R&D process without the expense of buying several different sets of tools or the time needed to change complete sets of tooling or turret speed.
Coperion K-Tron can provide single source solutions for all feeding and conveying needs in the pharmaceutical and nutraceutical industries. The complete Coperion K-Tron line of pharmaceutical equipment is engineered to meet the rigid requirements of the industry.
The ZSK 18 MEGAlab laboratory extruder is the smallest member of the ZSK family. This targeted and further development of proven ZSK technology extends the performance range of the series for R&D and production.
Coperion K-Tron vacuum sequencing receivers are designed to high quality standards for pneumatically conveying powders, pellets and granular materials for the bulk material handling industries.
Coperion K-Tron provides a variety of control options to meet a client's process needs. From standard equipment controls to interface options for both the pneumatic conveying systems as well as feeder controls, Coperion K-Tron is dedicated to ensure the client's specific process control requirements are met.
With over 100 years of experience in feeding technology, Coperion K-Tron development and engineering teams are experts at creating smart feeding solutions. Without consistent, dependable feeder accuracy and repeatability for your process, the integrity of any recipe—and hence the final product—will be compromised.
Coperion K-Tron's machine controllers and operator interfaces deliver full functional flexibility and the connectivity you need. Coperion K-Tron’s SmartConnex control environment provides comprehensive control capability with maximum flexibility and connectivity for systems up to 24 weigh belt feeders, loss-in-weight feeders, volumetric feeders, batchers, flow meters, Bulk Solids Pump (BSP) feeders or PID controlled devices as well as pneumatic refill systems.
