Newsletter | September 24, 2024

09.24.24 -- Are You Taking The HPCs In Your ADCs Seriously?

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Building upon 30+ years of experience in Highly Potent API (HPAPI) and complex API production, with continued investment and capacity expansion MilliporeSigma is an industry leader and reliable CDMO partner with the expertise and capabilities to tackle the unique challenges of these powerful compounds and the most intricate and potent API projects. The Madison/Verona site is one of the first facilities to receive SafeBridge®️ certification and the world's largest single-digit nanogram OEL containment facility. More.

INDUSTRY INSIGHTS

Training Biomanufacturing Operators Faster And More Effectively

Could a new approach to operator training help minimize batch loss? Learn how blended learning can enhance training effectiveness and engagement, reducing human error in your production line.

Accelerated Development: Gene Therapy Vs. Small Molecule

Combined with the inherent difficulty of the chemistry behind gene therapy development, its pace, structure, and funding dynamics are unique among treatment modalities.

Optimizing Nest Design To Streamline Fill And Finish Of RTU Cartridges

An optimized nest design for pre-fillable cartridges was designed using numerical simulation and data analytics, improving efficiency in pharmaceutical production.

Single Unit Dose Nasal Spray Carton Provides Cost Savings

Gain insight into how switching to a single-unit dose nasal sprayer carton reduced one company's material costs and significantly improved environmental sustainability throughout the product lifecycle.

Four Trends Redefining The Life Sciences Industry

The COVID-19 crisis acted as a catalyst for digital transformation in the healthcare industry. Learn how this transformation has impacted trends and new possibilities in the life science sector.

Checkweigher Provides High-Throughput Tube Line Automation Inspection

Teligent produces a range of generic prescription topical and injectable pharmaceuticals. To automate inspection on their high-throughput tube line, they turned to a dual-lane checkweigher.

Overcoming Melt Processing Challenges

Discover how a biodegradable polymer platform, easily applied with hot melt processing, enables processing at a relatively low temperature while preserving the potency of temperature-sensitive APIs.

Harnessing Analytical Development To Empower Process Development

This presentation addresses the critical need for high-throughput, reliable analytical development strategies to support expedited Investigational New Drug (IND) applications.

The Oligonucleotide Purification And Concentration Checklist

As the demand for oligonucleotides (oligos) increases in research, therapeutics, and drug development, so does the need for advanced technologies to enhance oligo manufacturing workflows.

Overcome Complex Protein Challenges With Optimized Expression

Realizing the potential of next-generation molecules calls on appropriate expression technologies and development processes that can facilitate their path to market.

FEATURED EDITORIAL

Are You Taking The HPCs In Your ADCs Seriously?

The wave of ADC (antibody-drug conjugate) development and manufacturing activity we’re currently witnessing, and importantly, the HPC (high-potency compounds) comprising the payloads in these therapies, demand thorough assessment of development and manufacturing facility design.

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Webinar: Achieving Manufacturing Efficiency In OSD Manufacturing

Join us October 16th at 11am to cover key concepts to improve your OSD manufacturing efficiency. Topics include characterizing formulations using instrumented tablet presses, the importance of tablet cup configurations, and the key scalability parameters for proper scale-up and product transfer. Together, these concepts can help you achieve consistent manufacturing outcomes, meet regulatory standards, and improve patient compliance and consumer satisfaction. Click here to learn more.

SOLUTIONS

Contract Manufacturing Capabilities

Commercial/Clinical cGMP Quality Control Analysis

Compliance Support With An Advanced HPLC System

Used Beckman Coulter Access Immunoassay System

Biocatalysis For Cost-Efficient, Environmentally Friendly Manufacturing

Seamlessly Integrating An E-WorkBook With A Customer's LIMS

Solid Form Services

Designed For Inhalation: Pulmonary And Nasal Delivery

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