Alconox Educational articles and resources
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The Benefits of Aqueous Critical Cleaning In Manufacturing
The use of aqueous cleaning in medical device manufacturing can provide numerous benefits in terms of efficacy, minimal surface contact and reduced residue potential, and easier cleaning validation.
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Detecting Residues In Cleaning Validation
When beginning cleaning validation, a company must identify the residues to be tested and then select the best detection method.
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How To Choose Alkaline Or Acid Pharmaceutical Cleaners
A great deal is known about how pH affects aqueous critical cleaning. The first step is for you to identify the residue that needs to be removed and then determine the optimal pH range that will remove it.
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Determine The Right Method Of Aqueous Cleaning In Pharma Manufacturing
Discover methods for cleaning pharmaceutical manufacturing equipment including manual, spray, and immersion Clean-in-Place (CIP) systems while emphasizing the importance of proper cleaning.
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The Guide To Critical Cleaning
In this guide, you'll find a method-by-method review of critical cleaning procedures. Following are specific examples of applications for Alconox detergents in healthcare, pharmaceuticals, laboratories, electronics, precision manufacturing, environmental sampling, and food and dairy processing.
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Minimizing Surface Residues With Aqueous Cleaning
The benefits of employing aqueous cleaning in pharmaceutical manufacturing are numerous. Virtually any pharmaceutical manufacturing equipment from tablet press to a stainless steel mixing tank can achieve their defined critically clean criteria using aqueous cleaning. Typically aqueous cleaners are formulated to ensure maximal cleaning performance by using key ingredients such as surface active agents (surfactants) that are excellent wetting agents that allow the cleaning solution to penetrate into crevices while getting under soils to allow for removal. Often very dilute solutions of aqueous cleaner effectively removes even worst case substances off a variety of hard surfaces including stainless steel, glass, plastic, or porcelain. By Malcolm McLaughlin
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The 7 Most Important Questions To Ask When Selecting An Aqueous Cleaner
Today's aqueous critical-cleaning detergents are blended for specific applications. Substrate, degree of soil load, and cleaning processes are all important considerations when selecting a detergent.
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Factors To Consider When Cleaning Pharmaceutical Equipment
Typically pharmaceutical operations require transition from bench scale R&D to pilot studies to full-scale manufacturing.
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The Role Of pH And Residue In Pharmaceutical Cleaning
A great deal is known about how pH affects aqueous critical cleaning. Typically, alkaline cleaners are used on oily residues and acidic cleaners are used on inorganic residues.
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How To Detect Detergent Residue To Maintain Laboratory Accreditation Guidelines
The following test procedures are suitable for detecting detergent residues resulting from improper rinsing and can be used to meet laboratory accreditation guidelines and questionnaires such as the College of American Pathologist program of State water lab accreditation programs.