Application Notes & Case Studies

  1. Analysis Of Free Drug Content In Antibody-Drug Conjugate 6/18/2026

    Free drug content can compromise ADC safety and performance if not carefully measured. A multidimensional LC/Q-TOF workflow pairs SEC and reversed-phase separation to enable sensitive detection.

  2. Protein And Payload Stability Of Brentuximab Vedotin In Monkey Plasma 6/18/2026

    Examine an approach that enables precise measurement of protein and payload stability for antibody–drug conjugates in plasma, helping researchers better understand molecular behavior over time.

  3. Intact- And Peptide-Level Characterization Of T-DM1 In Vitro 6/18/2026

    A sensitive workflow that combines affinity capture and high-resolution mass spectrometry reveals how antibody-drug conjugates evolve under physiological conditions, offering deeper insight into their stability.

  4. Identification Of Conjugation Sites In An Antibody Drug Conjugate 6/18/2026

    A streamlined workflow enables confident mapping of lysine-linked conjugation sites in ADCs. See how integrated automation and high-resolution analysis simplify complex characterization challenges.

  5. Best Practices For Protein Analysis With An Analyzer System 6/18/2026

    Strong protein analysis relies on optimized preparation, buffer consistency, and precise method settings. Gain insight into how small changes in temperature, storage, or injection can impact accuracy.

  6. Comparing Two CE-SDS Systems Using NISTmAb 6/18/2026

    Fluorescence and UV detection deliver highly comparable results in protein capillary electrophoresis. See how both approaches perform across systems and what it means for protein analysis.

  7. Accurate mAb Sizing Using The NIST mAb As A Ladder 6/18/2026

    Improve your mAb sizing accuracy by integrating a well-characterized reference standard into your analysis workflows, which reduces variability and delivers more precise measurements.

  8. Direct Amplification Of Research Samples 6/15/2026

    Skip time-consuming extraction steps and achieve reliable qPCR results. Direct amplification methods help researchers detect respiratory pathogens more efficiently across saliva and nasal samples.

  9. Direct Amplification Of Cell Culture Samples 6/15/2026

    Skip extraction and move straight to amplification with a streamlined qPCR workflow. Achieve comparable performance across multiple targets while reducing costs and saving time.

  10. HPAPI Containment: A Full Lifecycle Safety Innovation 6/15/2026

    Containing highly potent APIs across a full operational lifecycle requires a structured approach that addresses hazard scoring, quality by design, performance testing, and safe enclosure disposal.