Cleaning, Sterilization & Bio Decontamination White Papers & Case Studies

  1. QbD's Role in Pharmaceutical Solid Dose Dry Granulation

    The Pharmaceutical industry is undergoing change. Under fire by political pressures to drive down the cost per tablet, compounded by new drug discovery becoming more challenging escalating research costs, therefore, the industry is looking to unleash its efficiency shackles of the past.

  2. Major Nutritional Supplement Manufacturer Increases Production With New Mixing And Blending System

    A major nutritional supplement manufacturer needed to address the need for greater efficacy and additional capacity in the production of various products. Custom Powder Systems manufactured a 5000 Liter blender that fits and can be loaded and discharged within their limited manufacturing space and low ceiling heights.

  3. Integration Of Tray Dryers & Nutsche Filter In Containment Isolator System

    Walker Barrier Systems was tasked with providing a system to contain potent and toxic active pharmaceutical compounds to 0.5μg/m³ exposure level (TWA over operation duration), for an existing Lab space. The unit was designed for product filtration, drying in vacuum heat oven, hand sieving and discharging and final dispensing for further processing, using a Hicoflex system, for an existing Laboratory. By Gary Partington

  4. Unither Pharmaceuticals Deploys Fully Automated Production Line

    Unither is a world leader in the manufacture of formulations for the pharmaceutical industry. Its plant at Gannat, in the Department of Allier, is a specialised production site for manufacture of pharmaceuticals.

  5. Fumigation Within A Pharmaceutical Aseptic Filling Line

    Bioquell's Room Bio-Decontamination Service was required for a major multi-national pharmaceutical company needed a solution that woul removed Staphylococcus edpdermidis from specific zones in an aseptic filling line with areas ranging from European GMP Grade A to Grade D. The solution neeeded to meet FDS regulatory requirements and have proven efficacy documentation againt S. epidermidis.

  6. Decontaminate A Pharmaceutical Production Facility In Less Than 24 Hours

    Bioquell's Room Bio-Decontamination Service (RBDS) was the only solution for the a major multinational pharmaceutical company that required their production lines within a European manufacturing facility to be sterilized in a short period of time.

  7. Surrogate Testing Of A Downflow Booth Complete With Integrated Tray Dryer

    Walker Barrier Systems was tasked with providing two downflow booths, each with integrated tray dryer (client provision) mounted in the side wall. The booth was to be used for filling trays with wet cake, as well as the dispensing of dried product from the trays into drums using a custom designed “tray dispensing hopper”.

  8. A Complete Cost-Effective Solution For Washing And Sterilizing Animal Cages

    Design and deliver a complete cost-effective solution for washing and sterilizing animal cages with full backup of all process equipment. Use the equipment process chambers as chemical decontamination pass-through.

  9. Innovative Valve Interfaces Ensure Customized Productivity In B. Braun LIFE Nutrition Plant

    B. Braun Melsungen AG is one of the leading companies in the international pharmaceutical and medication sector. With an investment of 164 million Euros the company is currently building the LIFE Nutrition plant, one of the world’s most modern production sites for innovative nutrition solutions, at the company headquarters in the North Hessian city of Melsungen. Jens Voigtländer, Editor

  10. Pasteurization In A Laboratory Glassware Washer

    Typically, pasteurization is performed with a benchtop pasteurization system in a stove-top immersion bath. Bottles are immersed in boiling water and held at temperature for a given amount of time. The problem is while the immersion process is inexpensive, it is neither accurate nor controlled, and the benchtop equipment can be expensive and complicated to install and operate. A solution is the laboratory glassware washer which simulates tunnel washer conditions— i.e. the bottles are sprayed with water at a certain temperature.