Cleaning, Sterilization & Bio Decontamination White Papers & Case Studies

  1. White Paper: Current Methodologies & Chemistries Utilized In Effective Passivation Procedures 2/8/2005
    Chemical cleaning and passivation treatments on stainless steel tubing and equipment are an important aspect in the preparation of surfaces used in corrosive and critical environments. The formation of a higher chromium to iron (Cr/Fe) ratio in the passive layer will result in improved corrosion resistance and lowered rates of iron oxide formation (rouge)...
  2. Safety Is Not An Option - Improved Principles of Biological Safety Cabinet Design

    Effective Biological Safety Cabinet performance can be greatly affected by different laboratory conditions: Size of laboratory, location of cabinet within a room, traffic patterns of laboratory personnel, electrical variations, airflow ducts and grills, and other equipment. The greater the extremes, the increased likelihood a cabinet will pass-the safer the cabinet design.

  3. Pharmaceutical Cleaning Strategies: Develop A Quality Procedure

    There are many aspects to be considered when approaching the issue of pharmaceutical cleaning. First of all, one has to consider where to perform cleaning activity: in-place (CIP) or out-of-place (COP).

  4. How To Choose Alkaline Or Acid Pharmaceutical Cleaners

    A great deal is known about how pH affects aqueous critical cleaning. The first step is for you to identify the residue that needs to be removed and then determine the optimal pH range that will remove it.

  5. Interpreting The Results After A Chemical Decontamination Cycle Performed With Vaporized Hydrogen Peroxide

    The unexpected growth of a biological indicator (BI) at the end of a decontamination cycle is certainly an undesirable and problematic event.  What can and should be done at this point?

  6. The Guide To Critical Cleaning

    In this guide, you'll find a method-by-method review of critical cleaning procedures. Following are specific examples of applications for Alconox detergents in healthcare, pharmaceuticals, laboratories, electronics, precision manufacturing, environmental sampling, and food and dairy processing.

  7. Minimizing Surface Residues With Aqueous Cleaning

    The benefits of employing aqueous cleaning in pharmaceutical manufacturing are numerous. Virtually any pharmaceutical manufacturing equipment from tablet press to a stainless steel mixing tank can achieve their defined critically clean criteria using aqueous cleaning. Typically aqueous cleaners are formulated to ensure maximal cleaning performance by using key ingredients such as surface active agents (surfactants) that are excellent wetting agents that allow the cleaning solution to penetrate into crevices while getting under soils to allow for removal. Often very dilute solutions of aqueous cleaner effectively removes even worst case substances off a variety of hard surfaces including stainless steel, glass, plastic, or porcelain. By Malcolm McLaughlin

  8. Major Nutritional Supplement Manufacturer Increases Production With New Mixing And Blending System

    A major nutritional supplement manufacturer needed to address the need for greater efficacy and additional capacity in the production of various products. Custom Powder Systems manufactured a 5000 Liter blender that fits and can be loaded and discharged within their limited manufacturing space and low ceiling heights.

  9. CO2 Incubator Buying Guide — Key Considerations To Take into Account When Purchasing A CO2 Incubator

    CO2 incubators play a critical role in a wide range of clinical and life science research laboratories. They are designed to provide a reliable controlled in-vitro environment for optimum tissue cell culture growth.

  10. Applications And Integration Of Hydrogen Peroxide Vapor For Biotech/Bioprocess

    The increase in size and scale of bio-processing is presenting a new challenge. Traditional methods of sterilisation, to maintain clean facilities, are becoming difficult to deploy in a controlled and regulatory compliant way. By Richard Lucas, Ph.D., Bioquell UK Ltd.