Cleaning, Sterilization & Bio Decontamination White Papers & Case Studies

51. White Paper: Current Methodologies & Chemistries Utilized In Effective Passivation Procedures 2/8/2005
    Chemical cleaning and passivation treatments on stainless steel tubing and equipment are an important aspect in the preparation of surfaces used in corrosive and critical environments. The formation of a higher chromium to iron (Cr/Fe) ratio in the passive layer will result in improved corrosion resistance and lowered rates of iron oxide formation (rouge)...
52. How To Choose Alkaline Or Acid Pharmaceutical Cleaners

    A great deal is known about how pH affects aqueous critical cleaning. The first step is for you to identify the residue that needs to be removed and then determine the optimal pH range that will remove it.

53. Safety Is Not An Option - Improved Principles of Biological Safety Cabinet Design

    Effective Biological Safety Cabinet performance can be greatly affected by different laboratory conditions: Size of laboratory, location of cabinet within a room, traffic patterns of laboratory personnel, electrical variations, airflow ducts and grills, and other equipment. The greater the extremes, the increased likelihood a cabinet will pass-the safer the cabinet design.

54. QbD's Role in Pharmaceutical Solid Dose Dry Granulation

    The Pharmaceutical industry is undergoing change. Under fire by political pressures to drive down the cost per tablet, compounded by new drug discovery becoming more challenging escalating research costs, therefore, the industry is looking to unleash its efficiency shackles of the past.

55. Major Nutritional Supplement Manufacturer Increases Production With New Mixing And Blending System

    A major nutritional supplement manufacturer needed to address the need for greater efficacy and additional capacity in the production of various products. Custom Powder Systems manufactured a 5000 Liter blender that fits and can be loaded and discharged within their limited manufacturing space and low ceiling heights.

56. Integration Of Tray Dryers & Nutsche Filter In Containment Isolator System

    Walker Barrier Systems was tasked with providing a system to contain potent and toxic active pharmaceutical compounds to 0.5μg/m³ exposure level (TWA over operation duration), for an existing Lab space. The unit was designed for product filtration, drying in vacuum heat oven, hand sieving and discharging and final dispensing for further processing, using a Hicoflex system, for an existing Laboratory. By Gary Partington

57. Unither Pharmaceuticals Deploys Fully Automated Production Line

    Unither is a world leader in the manufacture of formulations for the pharmaceutical industry. Its plant at Gannat, in the Department of Allier, is a specialised production site for manufacture of pharmaceuticals.

58. Fumigation Within A Pharmaceutical Aseptic Filling Line

    Bioquell's Room Bio-Decontamination Service was required for a major multi-national pharmaceutical company needed a solution that woul removed Staphylococcus edpdermidis from specific zones in an aseptic filling line with areas ranging from European GMP Grade A to Grade D. The solution neeeded to meet FDS regulatory requirements and have proven efficacy documentation againt S. epidermidis.

59. Decontaminate A Pharmaceutical Production Facility In Less Than 24 Hours

    Bioquell's Room Bio-Decontamination Service (RBDS) was the only solution for the a major multinational pharmaceutical company that required their production lines within a European manufacturing facility to be sterilized in a short period of time.

60. Surrogate Testing Of A Downflow Booth Complete With Integrated Tray Dryer

    Walker Barrier Systems was tasked with providing two downflow booths, each with integrated tray dryer (client provision) mounted in the side wall. The booth was to be used for filling trays with wet cake, as well as the dispensing of dried product from the trays into drums using a custom designed “tray dispensing hopper”.