Cleaning, Sterilization & Bio Decontamination White Papers & Case Studies

51. Applications And Integration Of Hydrogen Peroxide Vapor For Biotech/Bioprocess

    The increase in size and scale of bio-processing is presenting a new challenge. Traditional methods of sterilisation, to maintain clean facilities, are becoming difficult to deploy in a controlled and regulatory compliant way. By Richard Lucas, Ph.D., Bioquell UK Ltd.

52. Integration Of Tray Dryers & Nutsche Filter In Containment Isolator System

    Walker Barrier Systems was tasked with providing a system to contain potent and toxic active pharmaceutical compounds to 0.5μg/m³ exposure level (TWA over operation duration), for an existing Lab space. The unit was designed for product filtration, drying in vacuum heat oven, hand sieving and discharging and final dispensing for further processing, using a Hicoflex system, for an existing Laboratory. By Gary Partington

53. Flexibility In Sterility Testing And Managing Risks Of False Positives

    This paper reviews the background to false positives and false negatives associated with the sterility test process. It explores the potential causes of such results and suggests methods of mitigation. By James Drinkwater, Bioquell UK Process & Compliance Director 

54. Unither Pharmaceuticals Deploys Fully Automated Production Line

    Unither is a world leader in the manufacture of formulations for the pharmaceutical industry. Its plant at Gannat, in the Department of Allier, is a specialised production site for manufacture of pharmaceuticals.

55. Top 10 Considerations When Selecting An Isolator Supplier

    While price is certainly an important reason for buying any piece of capital equipment, it is not always the top reason. There are important considerations to examine when selecting an isolator supplier.

56. Pharmaceutical Cleaning Strategies: Develop A Quality Procedure

    There are many aspects to be considered when approaching the issue of pharmaceutical cleaning. First of all, one has to consider where to perform cleaning activity: in-place (CIP) or out-of-place (COP).

57. Safety Is Not An Option - Improved Principles of Biological Safety Cabinet Design

    Effective Biological Safety Cabinet performance can be greatly affected by different laboratory conditions: Size of laboratory, location of cabinet within a room, traffic patterns of laboratory personnel, electrical variations, airflow ducts and grills, and other equipment. The greater the extremes, the increased likelihood a cabinet will pass-the safer the cabinet design.

58. How To Choose Alkaline Or Acid Pharmaceutical Cleaners

    A great deal is known about how pH affects aqueous critical cleaning. The first step is for you to identify the residue that needs to be removed and then determine the optimal pH range that will remove it.

59. Interpreting The Results After A Chemical Decontamination Cycle Performed With Vaporized Hydrogen Peroxide

    The unexpected growth of a biological indicator (BI) at the end of a decontamination cycle is certainly an undesirable and problematic event.  What can and should be done at this point?

60. Pasteurization In A Laboratory Glassware Washer

    Typically, pasteurization is performed with a benchtop pasteurization system in a stove-top immersion bath. Bottles are immersed in boiling water and held at temperature for a given amount of time. The problem is while the immersion process is inexpensive, it is neither accurate nor controlled, and the benchtop equipment can be expensive and complicated to install and operate. A solution is the laboratory glassware washer which simulates tunnel washer conditions— i.e. the bottles are sprayed with water at a certain temperature.