Cleaning, Sterilization & Bio Decontamination White Papers & Case Studies

71. The Role Of Biological Indicators For Hydrogen Peroxide Vapor Technology

    Biological indicators (BIs) have become the industry standard for verification of hydrogen peroxide vapor (HPV) decontamination efficacy. By Dr Lynne Murdoch, Bioquell UK Ltd

72. Designing An Effective Pharmaceutical Containment Blending System

    The same pharmaceutical Intermediate Bulk Container (IBC) that is used for shipping and storage can also be used for blending. 

73. A Strategy For Implementing Rapid Microbial Methods

    The purpose of this white paper is to present a strategy to be used and applied for rapid microbiological methods (RMM). By Gilberto Dalmaso, Sterility Assurance Consulting, A&L Co

74. Improve Efficiency In Bio-Contamination Control And Risk Mitigation

    There is a need to improve the efficiency in the pharmaceutical industry to meet new challenges of globalisation, competitiveness and the increasing diversity of products. By James Drinkwater

75. Biological Contamination Management In Aseptic Environments: Requirements And Expectations

    Bio-contamination found in critical zones within processing environments can affect the whole process and sterility of the final products, potentially putting patients at risk. This can lead to significant financial costs and impact operational resources. By James Drinkwater

76. Large-Scale Bio-Decontamination With Hydrogen Peroxide Vapor

    Use of hydrogen peroxide vapor (HPV) is a recognized and recommended solution for the decontamination of small aseptic processing enclosures. Due to the historic limitations and lack of understanding of this technology, other larger scale applications have often not been considered.

77. Flexible Measuring And Control In Reverse Osmosis Systems

    Reverse osmosis systems play a central part in water treatment. In industrial applications, for example, reverse osmosis is used for purifying process water, producing drinking water and desalinizing seawater or for producing ultra pure or pharmaceutical water. In addition to these processes, which aim at reducing the concentration of the substances dissolved in the water, the beverage industry also uses reverse osmosis systems for increasing concentrations, e.g. in the manufacture of fruit juice concentrates or for concentrating the must in wine production. By Christof Kundel, Segment Manager Water Treatment, Bürkert Fluid Control Systems

78. Achieving The Perfect Temperature Requirements for Blister Packaging

    When tablets are packaged in blisters, the plastic film must be the right temperature at the right moment: which is no easy task at an output of up to 1,300 blisters per minute. A customer-specific combination for proportional valve, temperature sensor and controller master is using the regulation of cooling water flow. If needed, machine developers can implement 13 parallel-working temperature control circuits. By Dr. Egon Huefner, Bürkert Fluid Control Systems

79. Making A Difference In Hygienic Processing – Elimination Of Dead Space Volume

    Thanks to high functionality within minimal space, multiport valves ensure compact processes, facilitate excellent cleaning and increase process reliability therefore contributing to improved product yield. By Marc Klingler, Segment Manager Hygienic Processing, Bürkert Fluid Control Systems

80. Challenges With Modern Oncology Drugs: Aseptic Preparation Of Cytotoxic Compounds

    This white paper focuses on the challenges facing modern oncology pharmacies concerning the aseptic preparation of cytotoxic drug compounds. It considers the current regulatory and health & safety issues faced by pharmacists and details some of the measures to tackle these problems, such as the use of isolator technology and the application of good manufacturing practice and quality risk management principles. Jane Metcalfe BSc (Hons), MSc, Field Applications Specialist, Bioquell UK Ltd