Cleaning, Sterilization & Bio Decontamination White Papers & Case Studies
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Fumigation Within A Pharmaceutical Aseptic Filling Line
Bioquell's Room Bio-Decontamination Service was required for a major multi-national pharmaceutical company needed a solution that woul removed Staphylococcus edpdermidis from specific zones in an aseptic filling line with areas ranging from European GMP Grade A to Grade D. The solution neeeded to meet FDS regulatory requirements and have proven efficacy documentation againt S. epidermidis.
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Decontaminate A Pharmaceutical Production Facility In Less Than 24 Hours
Bioquell's Room Bio-Decontamination Service (RBDS) was the only solution for the a major multinational pharmaceutical company that required their production lines within a European manufacturing facility to be sterilized in a short period of time.
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The Challenges With Real-Time Viable Particle Counters
While real-time viable particle counters offer significant potential benefits, they also present some new challenges to industry and regulators.
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Monitoring Chemical Processes For Early Fault Detection Using Multivariate Data Analysis Methods
Multivariate statistical methods can be used to monitor process variables and predict final product quality at an early stage, while also providing deeper understanding of the process. This allows engineers and production managers to optimize their processes, thereby realizing significant cost and time savings. By Dr Frank Westad, Chief Scientific Officer, CAMO Software
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Decontamination Comparison: Hydrogen Peroxide Vapor (HPV) vs. Ultraviolet Radiation (UVC)
The fundamental differences between these technologies, in terms of their mode of antimicrobial action and the method of delivery, result in a marked difference in microbiological impact. Bioquell HPV eradicates pathogens on hospital surfaces and achieves a 6-log sporicidal reduction in vitro.
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Hydrogen Peroxide Decontamination: Vapor Vs. Aerosolized Systems
When facing a microbial contamination challenge, hether from multidrug-resistant organisms in a hospital or in bio-pharmaceutical production facilities, not all hydrogen peroxide-based decontamination systems are the same.
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Aqueous Cleaning Of Petroleum Compounds From Laboratory Glassware
Petroleum compounds, such as refined hydrocarbon distillates, are generally a difficult-to-clean, oily, molasses-like substance.
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Variability In Sterility Test Processes And The Benefits Of Modular Workstations
This paper reviews some of the current operational practices that incorporate sterility testing and provides an insight into the role of hydrogen peroxide vapor bio-decontamination and continuous particle monitoring. By James Drinkwater, Bioquell UK Process & Compliance Director
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Advantages Of Gamma Irradiation For Effective Sterilization Methods
Many sterilization methods are available for pharmaceuticals, healthcare devices, and labware, including steam, sterile-filtration, ethylene oxide, vapor-phase hydrogen peroxide, electron-beam irradiation, and gamma irradiation. Each technique needs to be evaluated before use based on various criteria. Most importantly, one must consider how the technique will affect the final product characteristics and performance. By Betty Howard, Radiation TechTeam Manager, STERIS Isomedix Services
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Strategies For Gamma Sterilization Of Pharmaceuticals
A crucial step in pharmaceutical production is sterilization. There are many sterilization methods to choose from, such as steam, sterile filtration, ethylene oxide gas (EtO), electron beam (E-beam), and gamma radiation. Each technique has aspects that make it suitable or unsuitable for the sterilization of a particular product. By Ruth Garcia, Betty Howard, Rose LaRue, Glenn Parton, and John Walker, Steris Isomedix Services