Cleaning, Sterilization & Bio Decontamination White Papers & Case Studies

81. Making A Difference In Hygienic Processing – Elimination Of Dead Space Volume

    Thanks to high functionality within minimal space, multiport valves ensure compact processes, facilitate excellent cleaning and increase process reliability therefore contributing to improved product yield. By Marc Klingler, Segment Manager Hygienic Processing, Bürkert Fluid Control Systems

82. QbD's Role in Pharmaceutical Solid Dose Dry Granulation

    The Pharmaceutical industry is undergoing change. Under fire by political pressures to drive down the cost per tablet, compounded by new drug discovery becoming more challenging escalating research costs, therefore, the industry is looking to unleash its efficiency shackles of the past.

83. Challenges With Modern Oncology Drugs: Aseptic Preparation Of Cytotoxic Compounds

    This white paper focuses on the challenges facing modern oncology pharmacies concerning the aseptic preparation of cytotoxic drug compounds. It considers the current regulatory and health & safety issues faced by pharmacists and details some of the measures to tackle these problems, such as the use of isolator technology and the application of good manufacturing practice and quality risk management principles. Jane Metcalfe BSc (Hons), MSc, Field Applications Specialist, Bioquell UK Ltd

84. Use Of Hydrogen Peroxide Vapor Biodecontamination Technology For Facility Commissioning

    Whether it is a new laboratory research facility or renovation of an existing facility, a sound commissioning process is vital to start-up success. 

85. Hydrogen Peroxide Vapor Biodecontamination Technology: Are All Hydrogen Peroxides The Same?

    When deciding to purchase your first hydrogen peroxide vapor biodecontamination equipment, there are many factors to consider. One of these factors involves the type of hydrogen peroxide you will use as the sterilant in your equipment. By Arthur Papineau, BS ChE, MBA, Ben Gomez, BS BA, MBA, and John Klostermyer, PhD, STERIS Life Sciences

86. A Complete Cost-Effective Solution For Washing And Sterilizing Animal Cages

    Design and deliver a complete cost-effective solution for washing and sterilizing animal cages with full backup of all process equipment. Use the equipment process chambers as chemical decontamination pass-through.

87. Decontamination By Hydrogen Peroxide: Use And Technical Developments

    This article compares the concepts of sterilization, disinfection and decontamination with reference to the different scopes thereof. A technologically new method for the vaporization of the hydrogen peroxide and its dosage control is presented. 

88. Adding Up The True Costs Of A False Positive Sterility Test

    Use the following points to create your own list to examine just what aspects of ‘cost’ a false positive could be having on your business. They provide a base from which you can accurately determine the impact of false positives on your own production system. From this, you can begin to build a robust business case should you feel you need to mitigate risks for your own production process.

89. Essentials Of Moist Heat Sterilization Kinetics

    The F₀ algorithm was firstly introduced 1968 in the international practice of food industry, and proposed by FDA in 1976 for the pharmaceutical sterilization of Large Volume Parenterals: it is now officially included in most Pharmacopoeias.

90. Continued Process Verification Methods In Cleaning Validation

    An increasing interest in continued process verification has led to the spread of on-line assay methods in cleaning processes. This paper deals with two different on-line applications: conductivity sampling and the Total Organic Carbon analysis for washing machines.