Cleaning, Sterilization & Bio Decontamination White Papers & Case Studies

  1. Biological Contamination Management In Aseptic Environments: Requirements And Expectations

    Bio-contamination found in critical zones within processing environments can affect the whole process and sterility of the final products, potentially putting patients at risk. This can lead to significant financial costs and impact operational resources. By James Drinkwater

  2. Large-Scale Bio-Decontamination With Hydrogen Peroxide Vapor

    Use of hydrogen peroxide vapor (HPV) is a recognized and recommended solution for the decontamination of small aseptic processing enclosures. Due to the historic limitations and lack of understanding of this technology, other larger scale applications have often not been considered.

  3. Flexible Measuring And Control In Reverse Osmosis Systems

    Reverse osmosis systems play a central part in water treatment. In industrial applications, for example, reverse osmosis is used for purifying process water, producing drinking water and desalinizing seawater or for producing ultra pure or pharmaceutical water. In addition to these processes, which aim at reducing the concentration of the substances dissolved in the water, the beverage industry also uses reverse osmosis systems for increasing concentrations, e.g. in the manufacture of fruit juice concentrates or for concentrating the must in wine production. By Christof Kundel, Segment Manager Water Treatment, Bürkert Fluid Control Systems

  4. Achieving The Perfect Temperature Requirements for Blister Packaging

    When tablets are packaged in blisters, the plastic film must be the right temperature at the right moment: which is no easy task at an output of up to 1,300 blisters per minute. A customer-specific combination for proportional valve, temperature sensor and controller master is using the regulation of cooling water flow. If needed, machine developers can implement 13 parallel-working temperature control circuits. By Dr. Egon Huefner, Bürkert Fluid Control Systems

  5. Making A Difference In Hygienic Processing – Elimination Of Dead Space Volume

    Thanks to high functionality within minimal space, multiport valves ensure compact processes, facilitate excellent cleaning and increase process reliability therefore contributing to improved product yield. By Marc Klingler, Segment Manager Hygienic Processing, Bürkert Fluid Control Systems

  6. Challenges With Modern Oncology Drugs: Aseptic Preparation Of Cytotoxic Compounds

    This white paper focuses on the challenges facing modern oncology pharmacies concerning the aseptic preparation of cytotoxic drug compounds. It considers the current regulatory and health & safety issues faced by pharmacists and details some of the measures to tackle these problems, such as the use of isolator technology and the application of good manufacturing practice and quality risk management principles. Jane Metcalfe BSc (Hons), MSc, Field Applications Specialist, Bioquell UK Ltd

  7. Use Of Hydrogen Peroxide Vapor Biodecontamination Technology For Facility Commissioning

    Whether it is a new laboratory research facility or renovation of an existing facility, a sound commissioning process is vital to start-up success. 

  8. Hydrogen Peroxide Vapor Biodecontamination Technology: Are All Hydrogen Peroxides The Same?

    When deciding to purchase your first hydrogen peroxide vapor biodecontamination equipment, there are many factors to consider. One of these factors involves the type of hydrogen peroxide you will use as the sterilant in your equipment. By Arthur Papineau, BS ChE, MBA, Ben Gomez, BS BA, MBA, and John Klostermyer, PhD, STERIS Life Sciences

  9. Decontamination By Hydrogen Peroxide: Use And Technical Developments

    This article compares the concepts of sterilization, disinfection and decontamination with reference to the different scopes thereof. A technologically new method for the vaporization of the hydrogen peroxide and its dosage control is presented. 

  10. Adding Up The True Costs Of A False Positive Sterility Test

    Use the following points to create your own list to examine just what aspects of ‘cost’ a false positive could be having on your business. They provide a base from which you can accurately determine the impact of false positives on your own production system. From this, you can begin to build a robust business case should you feel you need to mitigate risks for your own production process.