Cleanroom Editorial and News

  1. Designing Precision Positioning For Vacuum Environments 9/4/2024

    The manufacture and calibration of UHV positioning systems is a complex task that sometimes pits design and maintenance considerations against the instrument’s technical performance.

  2. A Quality-Led Approach To Drug Production Facility Design 3/26/2024

    There are important considerations that architects and engineers can miss if they don't include the quality perspective. It's better to involve quality at the outset rather than discover omissions when it's too late.

  3. Experts' Advice On Facility Design And Construction 4/24/2025

    This is a review of the Pharmaceutical Online Live event “Facility Design And Validation Considerations For Drug Manufacturers," which featured industry experts Erich Bozenhardt and Herman Bozenhardt, as well as process architect Fred Grossfeld.

  4. Green Gains In Biopharma Without Closing Facilities? 2/29/2024

    Going green is virtually impossible for biopharma companies with legacy systems, but going greener might be within reach. Here are some ideas to get started.

  5. Optimizing Chromatography Media In Bioprocessing 10/26/2023

    How can you optimize your media for chromatography and improve consistency, yield, and purity through the integration of automation technologies such as advanced slurry preparation systems?

  6. ISO/DTR 14644 -21 Cleanrooms And Associated Controlled Environments 2/22/2024

    Here, we review the Technical Report outlining how particle counters are used to classify and monitor cleanroom performance, ensuring it meets required standards under normal operating conditions.

  7. The Crucial Role Of Cleaning In Effective VPHP Decontamination For Isolators 12/27/2024

    Effective isolator cleaning is crucial for vapor phase hydrogen peroxide (VPHP) decontamination. Proper tools, techniques, and training ensure sterility, and regulatory compliance.

  8. Ready-To-Use Containers: A Smart Approach To Fill & Finish Operations 8/25/2023

    RTU containers are in demand, as they are supplied pre-washed and pre-sterilized and can be integrated directly into aseptic Fill & Finish lines. Find out about the latest RTU containment solutions.

  9. Viral Vector Based Gene Therapy Drug Products: The Right Primary Container 5/20/2024

    Explore the major considerations for an ideal primary container for viral vector-based gene therapy drug products and the existing and new solutions in this space.

  10. What Is The Position Of Regulatory Authorities On PUPSIT? 5/2/2025

    PUPSIT and other integrity testing methods are crucial for manufacturers to reduce contamination risks and ensure drug product safety. Learn how your company can adhere to updated regulatory guidelines.