Material Handling Featured Articles

1. Solubility And Improved Patient Outcomes 9/9/2026

   Poor solubility poses major development challenges. Innovative formulation technologies and careful excipient selection can improve bioavailability and product performance.

2. How To Achieve Late-Phase Success In Complex OSD Development 8/31/2026

   Late-phase OSD scale-up demands more than technical know-how. This paper examines the frameworks, tools, and partnership models that determine whether promising molecules reach commercial production reliably.

3. Reducing Uncertainty In Early Oral Drug Development 8/31/2026

   Five recurring decision points in early oral solid dose development carry outsized downstream consequences. AI/ML-driven predictive modeling is reframing how teams manage those decisions under API and timeline constraints.

4. Lipid Formulation Development: Why Softgels Are The Technology Of Choice 8/31/2026

   Low bioavailability affects roughly 80% of APIs, yet many drug developers default to standard OSD forms. This paper examines why softgels deserve earlier consideration in formulation strategy.

5. 5 Hidden Risks In Early-Phase OSD Formulation Development 8/31/2026

   Early formulation decisions in OSD development carry risks that may not surface until later stages, when the cost of course correction is significantly higher.

6. Enabling Flexibility And Scientific Innovation In OSD Development 8/31/2026

   How one clinical-stage CNS biotech navigated early formulation complexity, shifting pipeline priorities, and scalable manufacturing demands through a strategic CDMO partnership.

7. July Update — U.S. Generic Drug Tariffs: Implications For Pharma And Outsourcing 8/7/2026

   Mathini Ilancheran updates us on how delayed U.S. tariffs on generic drug imports could reshape supply, sourcing, and trial planning.

8. Why Spray Drying Is Gaining Attention 7/20/2026

   Facing patent cliffs, pharma companies can leverage spray drying to reformulate complex biologics, enabling non-invasive delivery, boosting patient convenience, and securing new patents.

9. De-Risking Production Of Complex Oral Solid Dosages: Considerations & Key Capabilities 7/13/2026

   Reduce formulation and scale-up risk with integrated development and manufacturing expertise for complex OSD products.

10. The Future Of Continuous Is Integrated Manufacturing: The 4 Misconceptions About A Lean Process 6/2/2026

    Pharmaceutical continuous manufacturing is an enabler of better manufacturing, but only when implemented with intention.