Material Handling Featured Articles
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Considerations To Alleviate Sticking And Picking In Tablet Manufacturing
7/6/2022
Learn how compression tooling manufacturers can identify potential sticking and picking issues before tablet and tool designs have been finalized.
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How Tablet Shapes Impact Patient Acceptance
7/6/2022
Explore how a tablet's size, shape, and color can improve product appeal and influence consumer preference.
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How Long Should Tablet Tooling Last?
7/5/2022
Learn how you can prolong and protect your investment by evaluating the life of punches and dies.
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FDA Releases Pre-Launch Activities Importation Requests (PLAIR) Guidance
5/24/2022
The FDA has finalized the draft guidance describing the policy regarding requests for the importation of unapproved finished dosage form drug products by applicants preparing products for U.S. market launch based on anticipated approval of a pending NDA, ANDA, BLA, or combination product assigned to CDER.
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Small Molecule Drug Discovery: Can AI Do It All?
4/27/2022
The hope is that AI can solve the single most challenging problem at the heart of modern drug discovery: the reliable prediction of novel small molecule drugs that potently bind to a disease-causing protein and alter its function. This article discusses the challenges and how we can position ourselves to navigate them.
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6 Tips To Ensure Your NDA/BLA Is Ready For FDA Review
2/25/2022
When preparing a marketing authorization application for an NDA or a BLA, one aspect that is easily overlooked by small start-ups and mature multi-product drug sponsors alike is verification that all commitments made to the FDA have been completed and that evidence of this has been submitted to the agency.
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How To Make Solid Dose Pharmaceutical Tablets
2/24/2022
Here, we cover the basics of manufacturing pharmaceutical solid dose tablets that start out in a research and development independent lab, CDMO, or brand name manufacture.
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Factory/Site Acceptance Testing & Commissioning Responsibilities
2/22/2022
Execution of factory acceptance testing (FAT) and site acceptance testing (SAT) is a business-critical activity when it comes to commissioning of a new system or equipment. FAT is conducted at the equipment manufacturer’s site and SAT is conducted at the final site of installation. This article shares best practices.
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Media Selection For In Vitro Testing Of Poorly Soluble Drugs
10/26/2021
Lonza principle scientist Deanna Mudie Ph.D. covers the design of dissolution media to support biopredictive dissolution testing and how the properties of a drug and formulation affect performance.
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The Need For AI/ML In Drug Discovery, Dev, & Clinical Trials
10/25/2021
While an influx of new companies and technologies is spurring innovation in the industry, these startups are increasingly in competition for talent and capital. Although a fairly new area with respect to the use of AI, the drug design and development process is ripe for the application of machine learning and deep learning techniques.