Material Handling Products & Services

31. USP<1062> Tablet Compression Characterization 7/29/2024

    Natoli Scientific takes pride in its comprehensive USP<1062> Tablet Compression Characterization services, tailored to address the complexities of tableting in pharmaceutical manufacturing. Staying true to the parameters outlined in the United States Pharmacopeia (USP) Chapter 1062, our approach meticulously evaluates tablet compression behaviors. By thoroughly characterizing the compression profile, we can pinpoint the optimal compression force required to form a cohesive tablet without applying undue stress that could lead to capping — the separation of tablet tops during or after the compression phase.

32. Pharmaceutical Rotary Tablet Press: NP-255 7/11/2024

    Setting a New Benchmark for Ease of Operation

    The NP-255 is a robust tablet press that was built to meet even the most demanding needs of the mid-sized tableting industry. The press has features and options designed to increase production, improve tablet quality, reduce waste, and set a new benchmark for ease of operation. Designed, engineered, and manufactured in the USA, this unique machine has a maximum production speed of 192,000 tablets per hour.

    With a hardened steel die table, a gravity feeder that is interchangeable with a two-paddle forced feeder, and our industry-leading intuitive Natoli AIM™ ProPluscontrol system, the NP-255 is the new standard for value in the mid-sized tableting industry.

33. Oral Solid Dose Manufacturing 5/30/2024

    At Alcami, we provide cGMP manufacturing services that scale with your development and approval milestones, ensuring a seamless transition from clinical to commercial supply.

34. Outsourcing Your Dry Powder Preparation 5/2/2024

    Improve your manufacturing productivity with trusted weight powders.

    Increase throughput by outsourcing your dry powder preparation including supply, quality control, weighing and dispensing.

35. Used 30" Vector Hi-Coater Tablet Coating Pan 2/15/2024

    30" Vector Hi-Coater Coating Pan, stainless steel construction, for model VHC-1355 coater, built 2002.

36. Used GlobePharma Single Station Pharmaceutical Tablet Press 2/15/2024

    Used GlobePharma Single Station Tablet Press.

37. Powder Flow Properties & Characterization Services 1/31/2024

    Basic Powder Flow Characterization [USP <1174>]:

    A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.

    Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.

    When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.

38. Oral Solid Dose Formulation Assessment Services 1/31/2024

    Send a test sample of your powder to Natoli Scientific to get your formula characterized following USP <1062> Guidelines (Tablet Characterization Methods) that we have been practicing for over 25 years.

39. Oral Solid Dose Formulation And Lab Scale Capabilities 1/31/2024

    Natoli Scientific is dedicated to developing high-quality affordable products for your market needs.

    We provide a formulation design based on a strong scientific understanding and decoding interplay of materials and process parameters to ensure product integrity. We use traditional as well as principles of ‘Quality by Design (QbD)’ to develop robust lead prototype formulations. The early sound scientific investment in product development saves time and money during scale-up and commercial manufacturing.

40. OSD Pharmaceutical Tablet Manufacturing Services For Clinical Trials 1/31/2024

    Natoli Scientific offers manufacturing services of oral solids at a pilot scale and drug products for clinical trials.

    We also offer full-scale commercial manufacturing service till you are ready with your own manufacturing facility to avoid delay in the commercial launch.

    Team Natoli understands the complexity of the tablet manufacturing process over more than half a century. We are ready to shoulder every step of the tablet manufacturing chain from blending to granulation, to milling, to compression, to coating. Our manufacturing capabilities are backed up by our expert scientific team, who are ready to offer guidance in product development, technical transfers, and scale-ups.