Material Handling White Papers & Case Studies

  1. Predicting Food Effects In Oral Drug Delivery Using PBPK Modeling 7/15/2026

    Learn how integrated PBPK and molecular dynamics modeling predicted an ~11% fed-state Cmax increase for fenofibrate, giving formulation teams earlier, mechanistic insight into food-dependent absorption.

  2. Compaction Simulation For Tablet Technology Transfer And Scale-Up 7/15/2026

    Compaction simulation de-risked tech transfer for a 40 mg fexuprazan tablet by defining optimal roller compaction and lubrication parameters before scale-up. Access the full case study to see the data.

  3. Predicting Softgel Stability And Shelf Life Using Accelerated Modeling 7/15/2026

    Predict ibuprofen softgel shelf life in 21 days instead of years. ASAPprime modeling identified PEG-ester degradants as the limiting factor, estimating 5.5-year and 3.8-year shelf lives before long-term studies concluded.

  4. Predicting Drug-Loading Limits In Tablet Formulations 7/15/2026

    Learn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.

  5. Modeling Polymer Interactions To Improve Amorphous Solid Dispersion Stability 7/15/2026

    Molecular dynamics modeling revealed how hydrogen bonding between PVP and Eudragit drives stable amorphous solid dispersion formation, cutting formulation screening time significantly.

  6. Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement Strategies 7/15/2026

    In silico modeling cut through formulation guesswork for a compound with 0.015 mg/mL solubility, delivering an 8× Cmax and 5× AUC improvement and Phase I progression.

  7. Spray Dry Biologics For Oral Dosage Forms 5/15/2026

    Spray drying enables stable oral delivery of biologics by creating protective dry powders, improving bioavailability, stability, and targeted release compared with traditional formulation methods.

  8. The Importance Of Polymorph Screenings 5/6/2026

    Discover how systematic polymorph screening reduces development risk, safeguards product performance, and enables confident solid‑form selection across the drug development lifecycle.

  9. A Simple And Powerful Solution For Accelerating Dissolution 5/5/2026

    Many poorly soluble drugs fail not because of low solubility, but because they dissolve too slowly. Learn how focusing on dissolution rate can unlock absorption gains using simple strategies.

  10. Converting From A Spray-Dried Dispersion To A KinetiSol Formulation In <5 Months 2/26/2026

    A development team quickly turned a low‑bioavailability, high‑burden formulation into a streamlined, clinically improved version, boosting exposure, simplifying manufacturing, and accelerating progress.