Material Handling White Papers & Case Studies

  1. In-Situ, Non-Destructive Surface Area Measurement For The Optimal Application Of Lyophilization 10/2/2019

    A key focus of this paper is the relevant measurement of surface area, with experimental data demonstrating the performance and value of novel instrumentation for in-situ characterization.

  2. Manufacturer Finds Solution For Transporting HPAPI Product with Containment 7/10/2019

    Containment enclosure solution for an analytical weighing and solution-preparation operation involving HPAPI in powder form allows manufacturer to successfully transfer product from an enclosure to another enclosure.

  3. Venting Fume Hood Base Cabinets — A Better Way 3/27/2019

    Frequently, companies have used fume hood exhaust to ventilate hood base cabinets. There is both the need for this practice and the designs for them are frequently not well thought-out. 

  4. The Keys To Superior Containment In Compounding Applications 3/27/2019

    This paper reviews why very bad things happen when either quantity or purity of Highly Potent Active Pharmaceuticals is not properly maintained during the compounding process. 

  5. Increase Solubility And Bioavailability With Hot Melt Extrusion 3/22/2019

    When executed properly, HME advances poorly soluble compounds in the development pipeline, without adding delays, cost, or significant post-processing activities, and can scale to commercial manufacturing.

  6. Common Fume Hood Containment Problems 11/13/2018

    While there are “bad” fume hoods, anything wrong with the entire system (exhaust fan, ductwork, building configuration, regulative dampers) may cause a lack of containment in a hood.

  7. Pediatric Drug Product Development Through To Commercialization 1/9/2017

    Almac has developed a flexible pediatric dosage form consisting of minitablets filled into stickpacks using a robust manufacturing and filling process suitable for routine commercial manufacture.

  8. How A Placebo Formulation Is Designed For An Oral Solid Dose Product 4/15/2016

    Clinical studies on solid dose products may require a placebo.  The placebo, in the case of a tablet, should possess the same shape and color compared to the active product.

  9. In Vivo Study And The Impact Of The Dissolution Rate On Bioequivalence 2/5/2016

    Comparative human in-vivo study of an immediate release tablet over-encapsulated by gelatin and hydroxypropyl methyl cellulose capsules – impact of dissolution rate on bioequivalence.

  10. Medication Errors -- A Threat To Patient Safety: Mitigating Errors With Tablet Appearance 1/16/2014

    Medical prescription drug errors by doctors, pharmacists and patients account for 1.5 million incidences of sickness, injuries or deaths in the U.S. each year. By Jay Anbil and Steve Yoder