Material Handling White Papers & Case Studies

  1. An Easy-To-Swallow Depression Drug For Elderly Patients 4/20/2023

    Examine how an innovative formulation approach helped a developer create a version of their drug that promotes treatment compliance within the geriatric population.

  2. How Successful Tech Transfer Can Help Fast-Track NDA Approval 4/4/2023

    Examine the first-time-right tech transfer and phase-3 registration batch manufacturing process which led to a biotech receiving NDA approval for its novel compound followed by a successful commercial manufacturing partnership.

  3. Validated HPLC-UV Method For Quantification Of Paxalisib 1/18/2023

    Examine research into the development and validation of a HPLC method for the quantitation of paxalisib in mouse plasma and its potential use for routine therapeutic drug monitoring.

  4. Patient-Centric Oral Solid Dose Formulation 5/17/2022

    Gain insight into the systematic application of patient centricity to the design of OSD products.

  5. Hot Melt Extrusion: Improving Solubility Of Poorly Soluble Compounds 11/30/2021

    As you create your hot-melt extrusion (HME) strategy to manufacture amorphous solid dispersions (ASDs), there are several considerations to ensure your plan is flexible, robust, and comprehensive.

  6. In Vitro Dissolution Methodologies For Amorphous Solid Dispersions 10/25/2021

    With the availability of so many types of in vitro dissolution tests, how do you determine which one will be most effective in predicting in vivo performance of your BCS II or IV drug product?

  7. Product Development For Oral Solid Dose Using Continuous Manufacturing 10/30/2020

    A thorough evaluation using several small-scale studies should be completed to help determine whether continuous or batch manufacturing is the best fit for your product.

  8. Pediatric Dosage Form Considerations For Highly Potent Compounds 7/6/2020

    The development of pediatric medicine poses numerous challenges to pharmaceutical formulators, particularly products intended for infants and very young children. This white paper describes special considerations for selecting appropriate pediatric dosage forms and the benefits of choosing mini-tablets (e.g., orodispensible) for pediatric formulation, particularly for highly potent compounds.

  9. In-Situ, Non-Destructive Surface Area Measurement For The Optimal Application Of Lyophilization 10/2/2019

    A key focus of this paper is the relevant measurement of surface area, with experimental data demonstrating the performance and value of novel instrumentation for in-situ characterization.

  10. Manufacturer Finds Solution For Transporting HPAPI Product with Containment 7/10/2019

    Containment enclosure solution for an analytical weighing and solution-preparation operation involving HPAPI in powder form allows manufacturer to successfully transfer product from an enclosure to another enclosure.