MilliporeSigma Articles
-
Making MS-Based Glycan Analysis Easier
5/2/2022
Recent technological advances in mass spectrometry based methods have made it easier to overcome the challenges of glycoprotein analysis.
-
Combining Rapid And EP Bioburden Testing
5/2/2022
Review a procedure in which compendial testing is complemented by a simultaneous rapid test that uses an identical sample to generate much earlier results while allowing the compendial test to continue.
-
Studying Analyte Binding To Syringe Filters During Filter Validation
5/2/2022
Filter validation is a critical part of various pharmaceutical QC tests. Since QC tests require accurate analyte quantitation, analyte binding is an important factor.
-
Tips To Improve Size-Exclusion Chromatography For mAbs And ADCs
5/2/2022
In this article, we will explore tips to improve the method of size-exclusion chromatography (SEC), which is often used to measure monomer/aggregate and fragment content of mAbs and ADCs.
-
Pharma Analysis & Quality Control: Trends From The Rapid Pharma Evolution
4/4/2022
Discover how the pharma analysis and quality control community envisions future trends and if the challenges faced by your peers are the same as yours.
-
Robotics & Automation On The Brink Of Transforming Pharma QC
4/1/2022
In QC, there is still huge potential to accelerate the release of safe products. Here, we review ways to boost the reliability, data integrity, and productivity of microbiological testing.
-
Alternative Endotoxin, Non-Endotoxin Pyrogen Test Method
2/5/2021
The ability of the Mono-Mac-6 cell line to detect non-endotoxin pyrogens is sometimes questioned. To demonstrate its performance, tests have been performed using a wide panel of monocytic TLRs ligands.
-
Evaluating Pyrogen Contamination Risk And MAT In Pharmaceutical Processing
The measurement of pyrogens is an important safety measure for parenterally administered drugs. Here, we explore several advantages the Monocyte Activation Test (MAT) provides over the rabbit pyrogen test.
-
Neutralizers Of Disinfectants In Culture Media
This study investigates the efficiency of disinfectant-neutralizing agents added to culture media in the presence of several commercially available disinfectants.