Package Inspection Featured Articles

  1. How To Monitor The Performance Of Metered Dose Inhalers (MDIs) 10/21/2015

    The use of metered-dose inhalers (MDIs) for the treatment of diseases such as asthma has become popular since their introduction in the late 1950s. MDIs come in the form of nasal or oral inhalers and are much appreciated by patients who depend on them for their treatment. MDIs are designed to deliver precise/accurate and reproducible doses of the drug to the lungs or nose. This is crucial as patients rely on their inhaler to deliver the required medication at often crucial times when physical strength may be very low.

  2. Assembling The Package Integrity Profile For Autoinjectors

    Due to their complexity, combination products present unique challenges in implementing a container closure integrity (CCI) testing strategy. Learn about these challenges and how to overcome them.

  3. Ensuring IV Bag Sterility With Container Closure Integrity Testing Systems

    In the event of an IV bag leak, contaminants can adversely affect the solutions within. Learn how the reference standard for CCIT, USP 1207, applies to the CCIT inspection method of IV bags.

  4. Key Considerations For Selecting Flexible Fillers

    Flexible fillers are beneficial to drug developers looking for lifecycle management of their drug products. Explore key considerations for selecting flexible fill/finish manufacturing technologies.

  5. The Importance Of Container Closure Integrity (CCI) Feasibility Testing

    In the CCIT space, one single inspection technology cannot be used for every type of pharmaceutical product. You should always weigh the various factors to determine the ideal inspection methodology.

  6. Single-Use Manufacturing Systems: Implementation Considerations

    As single-use systems continue to evolve, more biopharma companies will be able to benefit from their ever-improving reliability and unique adaptability as part of both fully single-use and hybrid processes. 

  7. Evaluating Container Closure Integrity Of High-Risk Pharmaceuticals

    Manufacturing inconsistencies often result in container closure failure, causing serious implications down the supply chain. Learn why it is critical to use the most precise leak testing method possible.

  8. Selecting Container Closure Components: A Data-Driven Approach To CCI

    Discover an efficient, data-driven process that employs innovative methods to accelerate the selection of a closure containment system that meets the requirements of the modern regulatory landscape.

  9. Incorporating Lean Principles Into Pharmaceutical QC Laboratory Design

    This article presents a case study based on an international workshop hosted by Novartis Vaccines to prepare guidelines for incorporating lean principles into pharmaceutical quality control laboratory design. By Mike Dockery, Federico Gabardi, Javier Garay, Jim Gazvoda, Luke Kimmel, Pietro Orombelli, Christophe Peytremann, Tom Reynolds, Tanya Scharton-Kersten, Graham Shoel, and Jeanne Sirovatka

  10. Package Inspection Guidelines For Sterile Medical Products

    Class III medical devices have a unique set of requirements and package characteristics. Numerous inspection methods exist for medical package inspection that require a thorough understanding to ensure quality.