Package Inspection White Papers & Case Studies

1. Achieving Container Closure Integrity During Cryogenic Storage Conditions Using An Optimized Vial Stopper Combination 2/17/2022

   Here, we investigate possible primary packaging solutions for therapies requiring even colder storage temperatures down to cryogenic levels (-150°C to -180°C).

2. Detecting Integrity Breaches In A Range Of Pharmaceutical Blister Package Types

   Demonstrating the integrity of pharmaceutical blister packs is critically important, as any defects can affect the shelf life and efficacy of the contents. By Dr. D. Dixon, University of Ulster

3. Digital Color Inspection Optimizes Color Management In Packaging 6/5/2018

   Color is one of, if not the most critical component of a brand’s image, but it is also one of the most finicky and subjective components companies need to agree on.

4. Nitrogen Purge Optimization And Validation Of Sterile Liquid Filling Lines 12/27/2018

   Large molecule biopharmaceuticals can be prone to oxidation and to prevent this from occurring, the headspace is often purged with an inert gas during filling to ensure a longer shelf life.

5. Correlating Laser-Based Headspace Analysis To Helium Leak Rate Testing 5/22/2023

   Laser-based headspace analysis is a non-destructive and rapid method for testing container closure integrity. We demonstrate that headspace analysis is equally as sensitive as helium leak rate testing.

6. How To Properly Test Your Industrial Metal Detector 2/7/2019

   In this paper, we explain the differences between validation, verification and routine performance monitoring and give an overview of recommended test methods for different metal detection systems.

7. Replace Dye Ingress With Mass Extraction To Mitigate Risks 10/2/2018

   A major pharma company had a problem. Its manufacturing process engineers could not reliably verify that pouch packages were sealed properly. Product could potentially ship with questionable packaging.

8. Factors To Consider When Selecting A Vision Inspection System For Personal Care Products 3/5/2013

   Implementing a vision inspection solution to monitor the quality and security of your personal care product is an effective quality control method that allows processes to reach maximum throughput and productivity. By Wayne Eide

9. Root Cause Investigation Into A Possible Container Closure Integrity Failure 12/27/2018

   In cases where oxidation of the formulation causes discoloration and eventual degradation of the product, non-destructive headspace analysis tests can give deep insight into the root cause. Since the samples are not destroyed by the headspace analysis, further testing can be done to accurately correlate headspace conditions with other product characteristics.

10. Five Steps To Packaging Quality Assurance For Liquid Pharmaceuticals 3/16/2022

    Find solutions to five key challenges of quality assurance and information to help you identify which product inspection products can best support your application.