Package Inspection White Papers & Case Studies

1. How To Calculate The Total Cost Of In-Line Metal Detection Equipment

   Considering TCO helps to better understand the costs over and above the purchase price and also – when suppliers have differing offers – to compare them and ultimately to substantiate the investment decision.

2. Gene Therapy: Maintaining Sterility At Low Temperature Storage

   A gene therapy for pediatric Spinal Muscular Atrophy required a leak and break-resistant container which maintains sterility over product shelf life, through freeze and defrost cycles.

3. How To Select The Ideal Leak Testing Method For Your Application 6/15/2022

   Here, we present the pros and cons of electronic leak testing methods, their suitability for different leak detection applications, and professional advice on selection criteria.

4. CCIT Comparative Study Between Dye Ingress And Deterministic Methods 1/13/2023

   Explore the results of a unique comparative study of CCIT, and find a suitable deterministic test method to replace the blue dye test that follows the latest guidelines.

5. Root Cause Investigation Into A Possible Container Closure Integrity Failure 12/27/2018

   In cases where oxidation of the formulation causes discoloration and eventual degradation of the product, non-destructive headspace analysis tests can give deep insight into the root cause. Since the samples are not destroyed by the headspace analysis, further testing can be done to accurately correlate headspace conditions with other product characteristics.

6. Container Closure Integrity Testing: Risks And Methods 11/12/2018

   We share an overview of integrity tests where high sensitivity is required to prevent the risks of stability failure of highly moisture-sensitive drugs or biological ingress of sterile parenteral drugs.

7. Nitrogen Purge Optimization And Validation Of Sterile Liquid Filling Lines 12/27/2018

   Large molecule biopharmaceuticals can be prone to oxidation and to prevent this from occurring, the headspace is often purged with an inert gas during filling to ensure a longer shelf life.

8. Helium Leak Detection On Plastic Ophthalmic Containers 6/8/2023

   A major pharmaceutical entity wanted to ascertain their container system's seal quality. Explore results from a series of leak testing projects that highlighted key issues with their plastic containers.

9. Innovative Leak Testing Of Pharmaceutical Blister Packages 6/15/2022

   Learn how to obtain highly sensitive, quantitative measurements in real-time without specific tracer gases.

10. OEE And Product Inspection Efficiency In The Pharmaceutical Industry 6/4/2020

    Few industries are as heavily regulated as the pharmaceutical industry, as poor quality or otherwise defective pharmaceutical products can potentially have fatal results for end users. Manufacturers must perform a careful balancing act: weighing pressure to improve production speeds against the need to ensure compliance with government regulations. The purpose of this white paper is to provide an overview of the various components that go into measuring OEE, a method of obtaining a complete view of the efficiency of a production process, and then to discuss the ways in which product inspection equipment can affect OEE in the pharmaceutical industry.