Package Inspection White Papers & Case Studies

1. Cryogenic Storage Of IV Bags For Cell And Gene Therapies 12/18/2025

   Cryogenic storage can compromise packaging integrity for cell and gene therapies. Learn how vacuum decay technology detects micro leaks and ensures product safety under extreme conditions.

2. Trends In Pharmaceutical Leak Tightness Testing

   Great confusion exists in the definition and application of leak tightness. That confusion is a result of improper leak-tightness design specifications. 

3. Nitrogen Purge Optimization And Validation Of Sterile Liquid Filling Lines 12/27/2018

   Large molecule biopharmaceuticals can be prone to oxidation and to prevent this from occurring, the headspace is often purged with an inert gas during filling to ensure a longer shelf life.

4. Three Ways To Enhance Pharmaceutical Packaging Lines 8/1/2012

   This white paper focuses on optical character recognition (OCR) and its extensive use in pharmaceutical packaging for compliance with date and lot tracking regulations. Machine vision OCR helps manufacturers adhere to these mandates in an effi cient and cost-effective manner, and can also improve line performance.

5. Optimized Product Recovery Using The Drug Product Filtration System 1/12/2026

   Explore strategies to maximize drug product recovery during sterile filtration, minimize hold-up volume, and reduce dilution after PUPSIT to ensure higher yield, improved efficiency, and less waste.

6. Vision System Increases OEE By 200% On Pharmaceutical Packaging Line

   A major pharmaceutical manufacturer’s packaging line presents a challenging vision system application because of the need to select exactly the right label among dozens of possible alternatives needed to meet differing languages and regulatory requirements around the world.

7. Helium Leak Detection On Plastic Ophthalmic Containers 6/8/2023

   A major pharmaceutical entity wanted to ascertain their container system's seal quality. Explore results from a series of leak testing projects that highlighted key issues with their plastic containers.

8. Gene Therapy: Maintaining Sterility At Low Temperature Storage

   A gene therapy for pediatric Spinal Muscular Atrophy required a leak and break-resistant container which maintains sterility over product shelf life, through freeze and defrost cycles.

9. Development Of A Container Closure Integrity Test Method For Autoinjectors 9/30/2024

   Explore how a non-destructive method can be developed to test container closure integrity in autoinjectors equipped with an optically transparent window.

10. Aseptic Blow-Fill-Seal: A Sustainable Process For Packaging Pharma Liquids 10/17/2018

    Aseptic blow-fill-seal systems for packaging pharmaceutical liquids incorporate materials and processes that provide critical advantages for sustainable initiatives.