Package Inspection White Papers & Case Studies

  1. Case Study: Pharmaceutical CMO Uses X-Ray, Metal Detection And Checkweigher Systems To Achieve High Quality Standards 8/11/2011
    Pharma Tech Industries (PTI), a contract manufacturer and packer of pharmaceuticals, medical devices and personal care products, is focused on exceeding customers’ expectations. To consistently achieve their high quality standards, they rely on x-ray and metal detection systems from Mettler-Toledo Safeline and checkweighers from Mettler-Toledo Hi-Speed.
  2. Trends In Pharmaceutical Leak Tightness Testing

    Great confusion exists in the definition and application of leak tightness. That confusion is a result of improper leak-tightness design specifications. 

  3. Development Of A Container Closure Integrity Test Method For Autoinjectors 9/30/2024

    Explore how a non-destructive method can be developed to test container closure integrity in autoinjectors equipped with an optically transparent window.

  4. Correlating Stopper Height To Container Closure Integrity 11/21/2023

    Learn how to comply with the new EU Annex 1 Section 8.28. Here, we describe a typical raised-stopper investigation and demonstrate how to generate scientifically robust data using headspace analysis.

  5. Ensuring CCI For Products Requiring Deep Cold Storage By Correlating Seal Quality To CCI 3/3/2021

    This case study describes how packaging development and process study data of a pharmaceutical vial product requiring deep cold storage can be combined in a holistic approach.

  6. Replace Dye Ingress With Mass Extraction To Mitigate Risks 10/2/2018

    A major pharma company had a problem. Its manufacturing process engineers could not reliably verify that pouch packages were sealed properly. Product could potentially ship with questionable packaging.

  7. Digital Color Inspection Optimizes Color Management In Packaging 6/5/2018

    Color is one of, if not the most critical component of a brand’s image, but it is also one of the most finicky and subjective components companies need to agree on.

  8. Ophthalmic Product Package Inspection

    Ophthalmic products come in a variety of package formats. The liquid-filled packages are often soft containers with snap-on or screw caps, and include foil lidded blister packs for single-use contacts.

  9. Rapid Nondestructive Moisture Determination Of Freeze-Dried Product 12/28/2018

    Rapid water vapor determination with an optical method could replace the slow destructive traditional methods for the moisture analysis of freeze-dried product. A description of industry applications of headspace moisture analysis including freeze drying cycle optimization, lyo chamber moisture distribution mapping, and 100% moisture inspection of commercial freeze-dried product.

  10. Helium Leak Detection Vs. Dye Leak Testing 11/22/2022

    A global pharmaceutical entity was experiencing early package failures from stability studies for a new drug product. Learn about the solution and the results obtained from this case.