Package Inspection White Papers & Case Studies

  1. Container Closure Integrity Testing: Sensitivity, Automation, Efficiency 4/6/2020

    Explore the need for sensitive, reliable, and automated container closure integrity testing technologies, and how existing deterministic solutions can help achieve optimum quality assurance goals.

  2. Headspace Moisture Analysis For Determination Of Residual Moisture Content In Lyophilized Pharmaceutical Products 8/24/2021

    Here, we describe how rapid non-destructive headspace moisture determination enables the generation of insightful data for product life cycle activities.

  3. Root Cause Investigation Into A Possible Container Closure Integrity Failure 12/27/2018

    In cases where oxidation of the formulation causes discoloration and eventual degradation of the product, non-destructive headspace analysis tests can give deep insight into the root cause. Since the samples are not destroyed by the headspace analysis, further testing can be done to accurately correlate headspace conditions with other product characteristics.

  4. Nitrogen Purge Optimization And Validation Of Sterile Liquid Filling Lines 12/27/2018

    Large molecule biopharmaceuticals can be prone to oxidation and to prevent this from occurring, the headspace is often purged with an inert gas during filling to ensure a longer shelf life.

  5. Rapid Nondestructive Moisture Determination Of Freeze-Dried Product 12/28/2018

    Rapid water vapor determination with an optical method could replace the slow destructive traditional methods for the moisture analysis of freeze-dried product. A description of industry applications of headspace moisture analysis including freeze drying cycle optimization, lyo chamber moisture distribution mapping, and 100% moisture inspection of commercial freeze-dried product.

  6. A Complete Guide To Capsule Checkweighing 5/2/2025

    Understand why accurate capsule weighing is essential for therapeutic efficacy, safety, and adherence to pharmaceutical manufacturing standards.

  7. Bonfiglioli Establishing Relationships In All Industry Sectors With Leak Testing Solutions Pharmaceutical Online Interview With Giuseppe Bonfiglioli, President, Bonfiglioli Engineering 4/3/2007
    The editorial staff at Pharmaceutical Online recently sat down with Giuseppe Bonfiglioli, President, Bonfiglioli Engineering, to discuss how the company provides leak testing equipment to all sectors of the pharmaceutical manufacturing industry. Enjoy the discussion. Submitted by Bonfiglioli Engineering SRL

  8. How To Properly Test Your Industrial Metal Detector 2/7/2019

    In this paper, we explain the differences between validation, verification and routine performance monitoring and give an overview of recommended test methods for different metal detection systems.

  9. Cold And Ultra-Cold Vial Helium Leak Testing 11/22/2022

    A global pharmaceutical entity was comparing vials for helium leak testing services. Explore the results obtained from collecting and tabulating the helium leak rate data as well as the solution.

  10. Ensure Quality Control With Innovative Software 7/1/2025

    Ensure unmatched product quality with an X-ray system paired with an innovative software that detects contaminants and missing items in stacked packaged goods with precision.