Production Featured Articles

1. Viewing HEK293 Transient Transfection Through A Wider Lens 12/11/2024

   HEK293 transient transfection is a leading platform for gene therapies. However, manufacturing challenges remain, particularly in scaling up production. Let's examine some key aspects of the scale-up process.

2. Stage 3a: A Key Indicator For Process Validation Maturity 12/9/2024

   Process validation's stage 3a serves to reconfirm the assumptions made during design space development and is particularly pronounced for new modalities and emerging processes.

3. Chromatography Column Packing - MabSelect PrismA™ Resin 12/6/2024

   Proper packing for MabSelect PrismA resin is crucial to prevent issues like cracking or channeling which can lead to process disruptions and product loss.

4. Bayer's Supply Network-Centric Approach To Digitalization 12/5/2024

   Shifting away from paper records is the nonnegotiable first step toward implementing novel technology. Here's how one company is approaching the monumental task.

5. AstraZeneca's Digitally Connected Strategy For API Manufacturing 12/3/2024

   The company's packing in the latest technology at its APICOM facility in Dublin. A key feature is more effective and timely use of process data.

6. 2024 Survey Findings: How Is The "Lab Of The Future" Becoming Reality? 12/3/2024

   The Pistoia Alliance conducted a survey as a pulse check on which technologies the pharma/biotech industry is investing in and companies' progress integrating new tech into the lab.

7. The Status Quo Of Oligonucleotides Is Not The Future 12/2/2024

   The oligonucleotide field is booming, but manufacturing challenges loom. Experts discuss optimizing production for these promising therapies with flexible, sustainable, and high-yield approaches.

8. The 4 Technologies Poised To Transform The Pharmaceutical Supply Chain In 2025 And Beyond 12/2/2024

   These key technological advancements will significantly impact the pharma/biotech supply chain in 2025 and beyond. If you aren't implementing any of them yet, you may want to rethink your plans.

9. Defining When To Implement Technologies To Support Commercial Growth 11/20/2024

   Technology decisions must be understood in the context of your business strategy and projected milestones. With a framework in place, you can define what tech solution you need and when you need it.

10. Enteric Coatings For Oral Solid Dosages: A Short Guide 11/19/2024

    Enteric coatings play a pivotal role for drugs/APIs that need to withstand the harsh conditions of the stomach in order to dissolve in the intestine. This article shares an overview, commonly used excipients, and more.