Insights On Quality Assurance

  1. Quality Assurance Of Hotel Cosmetics

    Using checkweighers for 100% inline product control of bottles, jars and tubes.

  2. Container Closure Integrity Testing For Sterile Vial Products In Deep Cold Storage

    A vaccine-focused biotechnology company approached LIGHTHOUSE to help investigate a phenomenon observed in liquid vaccine product stored at -80°C. During QC testing, a number of vials were found to have an overpressure. This phenomenon represented a serious safety risk and LIGHTHOUSE was asked to support an investigation to identify the root cause.

  3. 10 Considerations For Balance Stability

    Stability of your weighing balance is paramount when it comes to collecting reliable data for project. As the old adage goes, “Anything that can go wrong will go wrong.”. Depending on the problem, taking obvious action for a seemingly obvious solution may not result in success. The purpose of this paper is to inspire thought and dialogue regarding those “not so obvious” sources of balance stability issues. Below, you may find 10 prompt questions that will hopefully guide one in resolving those pesky head-scratchers.

  4. Quality Assurance And Your CDMO

    While the end result of regulatory compliance with quality standards is binary, the processes employed to get there do not need to be rigid, prescriptive, inefficient, and expensive. Learn how an innovative approach drives lower costs and higher efficiencies.

  5. Stopper 'Pop-Up' And The Effects On Container Closure Integrity Of Freeze Dried Vials

    Stopper pop-up resulting in loss of container closure integrity is not uncommon and impacts the stability, sterility and reconstitution of lyophilized product. Non-destructive headspace analysis is a powerful method for monitoring container closure integrity in finished vials of freeze dried product and for building quality into the manufacturing operation.

  6. In-Process Monitoring Of Headspace Oxygen Levels In Parenteral Containers

    Using a high sensitivity detection technique known as Frequency Modulation Spectroscopy (FMS), LIGHTHOUSE rapid non-destructive headspace oxygen inspection can help streamline the monitoring of purge performance on the filling line. This paper demonstrates the correlation of the FMS rapid non-destructive technique for analyzing headspace oxygen levels with the most commonly used conventional destructive techniques for headspace oxygen inspection.