Weiler Engineering’s ASEP-TECH^® Blow/Fill/Seal machines are ideal for processing temperature sensitive products such as biological and protein-based materials – providing a level of enhanced sterility assurance.

Large volume humidifiers and nebulizers – typically in sizes from 250 – 1000mL – can be specifically designed to fit existing delivery devices. Custom designs to facilitate the control of humidification in oxygen delivery can be developed.

ASEP-TECH® Blow/Fill/Seal systems are ideally suited for packaging injectable products, including small-volume and large-volume parenterals. Containers are formed, filled, and sealed in one compact machine frame, eliminating many of the steps and additional expenses of conventional processing. Blow/Fill/Seal containers offer tremendous advantages over glass, including weight savings, particle-free processing, resistance to breakage, ease of opening, and recycling capability.

A small-scale production-capable blow/fill/seal system for laboratory, stability/clinical trial, 503b, vaccine, and biologic. Extremely versatile with a small footprint, the machine can be configured for single-use technology (SUT) or CIP/SIP (clean-in-place/steam-in-place).

Unit dose blow/fill/seal vials for one-time ophthalmic use have become an accepted international standard for pharmaceutical manufacturing and packaging. The ASEP-TECH Advantage is reflected in the development of formulations that no longer contain preservatives, minimizing the risk of allergic reactions for patients.

The ASEP-TECH system can include the application of insertion technology to permit the incorporation of a tip and cap insert into the blow/fill/seal package to produce a calibrated drop.

The ASEP-TECH® system produces a package that remains hermetically sealed until its point of use. Emergency eye wash stations utilize a blow/fill/seal container, typically 12 to 16 ounces, with a twist-off or snap-off top for quick dispensing of sterile water or saline in industrial and laboratory applications.

Spike top containers are used for many over-the-counter eye care products – including “red eye” and “dry eye” formulations – for multiple dosing in the 5 to 20 mL range. This type of Blow/Fill/Seal package is extremely cost-effective and produces an enhanced level of sterility assurance for the consumer.

Applications for Small Volume Parenterals include local anesthetics, vaccines, and other traditional injectable products. The 10 to 100 mL range is typically designed for multi-dose applications.

Weiler Engineering offers blow/fill/seal packaging machines to cover virtually every segment of the respiratory therapy marketplace – from simple inhalation solutions to complex delivery systems for deep lung and nasal applications.

Unit dose blow/fill/seal vials for one-time ophthalmic use have become an accepted international standard. The ASEP-TECH Advantage is reflected in the development of formulations that no longer contain preservatives, minimizing the risk of allergic reactions for patients.

Insertion technology for ASEP-TECH® Blow/Fill/Seal systems was pioneered by Weiler Engineering, Inc. The technology incorporates the use of a barrier isolator, typically located outside the machine room and integrated with the BFS machine.

Weiler Engineering, Inc. manufactures both fully automated and manual load pharmaceutical cap welding systems to mate with the ASEP-TECH® Blow/Fill/Seal machines to produce a multi-entry insert format for LVPs.

Weiler Engineering’s Blow/Fill/Seal machines excel in packaging of liquid oral supplements and additives.

Large Volume Parenterals are typically injectable products designed for intravenous delivery applications. The large volume parenteral bottles are most often produced from a resin that can be autoclaved, either at 106° C or 121° C.

ASEP-TECH Blow/Fill/Seal machines are designed and manufactured by Weiler Engineering offers a unique combination of world-class engineering, leading-edge automation and process design, assures years of reliable, high quality production.

The ASEP-TECH® System automatically delivers a finished package in five steps

ASEP-TECH® Blow/Fill/Seal machines are designed and manufactured by Weiler Engineering, Inc. in Elgin, Illinois for process manufacturing needs.

Weiler Engineering is a leading provider of aseptic Blow/Fill/Seal liquid packaging machines for pharmaceutical and healthcare applications. The continuous incorporation of the latest technological advances in equipment design and systems assure our customers of the highest level of quality in the production of sterile liquid products.

The ability to provide sterile liquid products that meet corporate, scientific, regulatory, and end-user requirements can be a demanding task in today's environment. Through your implementation of ASEP-TECH® Blow/Fill/Seal technology, these application challenges can be met by the creative container and closure designs available with each system.