Application Notes & Case Studies

  1. End-To-End, GMP Production Platform For Synthon’s Biologics Pipeline
    4/28/2017

    “The engineering principles represented in the Sartorius bioreactor portfolio were essential in the smooth scale-up of cell culture from lab scale to a disposable 2000L reactor. Face-to-face meetings were instrumental in the design and quick implementation of all process equipment.” – Synthon

  2. Texture Analysis: Comparison Of Moisturizing Cream By Back Extrusion
    4/25/2017

    Moisturising creams serve to keep the skin feeling smooth, soft, and looking radiant and healthy by retaining moisture or water in the outer most skin layer. Different moisturising creams will be defined by their viscosity or thickness. Formulating moisturising creams therefore largely depends upon the required end product consistency, influencing the choice of material to use.

  3. Optimizing Small Batch Size To Solve Formulation Challenges
    4/25/2017

    If current manufacturing practices are followed to handle small batches of API on industrial size machines, it results in handling difficulties and lower product yield.

  4. A Pediatrics Practice Tracks Vaccine Temperatures With BLE Data Loggers
    4/20/2017

    A Louisiana concierge pediatrics practice employs Onset InTemp Bluetooth Low Energy vaccine temperature loggers to ensure patient safety.

  5. OptiForm® Solution Suite: Improved Bioavailability Of Trio Medicines TML-2 In 12 weeks
    4/11/2017

    Trio Medicines Ltd (Trio) is a London-based pharmaceutical company, founded in 2005. Trio is developing treatments for unmet medical needs, including rare diseases, with the aim of improving the health and quality of life of patients worldwide. Trio’s lead compound TML-2 is the acetyl prodrug of TML-1, a novel, well tolerated G-protein coupled receptor antagonist which shows clinical promise but has limited bioavailability owing to low solubility. The prodrug approach was only partially successful in increasing the solubility and bioavailability of TML-1, so Trio turned to Catalent for help. Utilizing OptiForm Solution Suite platform, Catalent’s experts screened 3 formulation technologies, and provided 4 formulation prototypes, in only 12 weeks. In 3 of the 4 prototypes, bioavailability of TML-2 was enhanced substantially.

  6. Texture Analysis: Testing Viscosity Of Creams
    4/10/2017

    Moisturising creams serve to keep the skin feeling smooth, soft, and looking radiant and healthy by retaining moisture or water in the outer most skin layer. Different moisturising creams will be defined by their viscosity or thickness. Formulating moisturising creams therefore largely depends upon the required end product consistency, influencing the choice of material to use.

  7. Ensuring IPC And QC of Final Products In Pharmaceutical Production
    4/7/2017

    Density measurement is a powerful and important method to ensure in-process control (IPC) and quality control of final products in pharmaceutical production facilities or, more specific, in a hospital pharmacy’s daily routine.

  8. Meeting US Pharmacopeia Standards For Triethyl Citrate
    4/7/2017

    Anton Paar's Generation M density meters and Abbemat refractometers deliver accurate and repeatable measurement results while providing system security for 21 CFR Part 11 compliance.

  9. High Potency Containment For Polypeptide Vaccine Manufacturing
    4/5/2017

    The team at Polypeptide Labs' overall project aim was to achieve homogenization (blending/tumbling) of potent lyophilized polypeptide product offloaded from a separate isolator.

  10. A&Z Pharmaceutical Improves Accuracy With Checkweigher Technology
    3/31/2017

    A&Z Pharmaceutical improved their production efficiencies, selecting an unusual chute-fed checkweigher, which helps ensure final product quality, reduce labor and speed production.