Application Notes & Case Studies

1. Reducing Cycle Time By 88% Through Strategic Solvent Replacement In Pharmaceutical Development 10/14/2026

   Replacing methylene chloride in a slow, labor-intensive API step led to a single-solvent, one-pot process with a shorter reaction time and improved yield and purity.

2. Crude Peptide Purification Optimization For Scalable Manufacturing 10/7/2026

   Transitioning lentiviral vectors to final drug product raises quality demands. A simplified membrane-based capture step minimizes downstream losses that can constrain systemic dosing.

3. Reduce Complexity, Not Quality In CAR T Cell Manufacturing 9/29/2026

   Fragmented CAR T cell manufacturing workflows drive up costs and extend timelines. This case study quantifies what consolidating manufacturing and QC through automation actually delivers.

4. Characterization Of PFAS Extractables In Gas Filtration Devices 9/29/2026

   Understand how fluorinated membrane chemistries in sterilizing grade gas filters may introduce PFAS risks, and how extractables testing can support contamination control strategies.

5. Imprints On Oral Solid Dosage Forms 9/28/2026

   Selecting the right tablet imprinting technology is essential for product identification and compliance. Improve your print clarity, speed, and overall manufacturing efficiency.

6. Formulation And Process Challenges For A Needle-Shaped API 9/28/2026

   Managing challenging active pharmaceutical ingredient crystal structures and choosing dry granulation over wet granulation requires strategic processing choices.

7. From Sequence To Scale In Seven Months 9/26/2026

   Accelerate recombinant protein development from sequence to scale while maintaining stable expression, manufacturing efficiency, and critical quality attributes.

8. Manufacturing Glycosylated Erythropoietin Without 𝛼1,3-Fucosylation 9/26/2026

   See how expression hosts affect recombinant EPO glycosylation, bioactivity, and consistency, with reproducible N-glycan profiles and absence of α1,3-linked fucosylation.

9. Characterization Of Fly-Derived Prolactin: Insights Into Glycosylation And Activity 9/26/2026

   Explore how D. mel-derived human prolactin (hPRL) compares with hPRL expressed in E. coli and HEK293 cells through detailed physico-chemical and biological characterization.

10. Characterizing Protein Stability By DSC 9/24/2026

    Discover how differential scanning calorimetry quantifies the thermodynamic forces behind protein folding and stability, providing valuable insight for protein engineering and therapeutic formulation.