Application Notes & Case Studies

  1. Replicating An Aspirin And Related Substances Method On An Arc HPLC System 6/29/2022

    We demonstrate method transfer and migration between instruments that successfully replicates methods, producing equivalent chromatographic separation and analytical results generated by the method to the results obtained on the comparable LC systems.

  2. How To Perform HPLC Method Transfer Between Different Analytical Testing Equipment 6/27/2022

    It is essential for the analytical laboratories to successfully transfer analytical methods. We present a transfer of the HPLC method for related substances analysis of metoclopramide HCl.

  3. Risk-Based Approach Supports Migration Of Legacy Methods For Eurofins BPT Toronto 6/27/2022

    Eurofins Bio-Pharma Product Testing applied a modern, risk-based approach to method migration and was able to understand the impact of introducing state-of-the-art technology for their legacy methods.

  4. Method Migration Of Size-Exclusion And Ion-Exchange Methods For mAb Analysis From HPLC To Modern UHPLC platform 6/24/2022

    Although development and quality control laboratories may be slow to replace existing technologies, modern technologies can benefit legacy methods and future development activities as part of lifecycle management.

  5. Efficient-Pro Medium And Feeds Deliver Strong Product Quality While Enhancing Productivity In CHO-K1 And CHO-S Cells 6/20/2022

    Early identification of a robust, commercially available, optimized platform medium and cell line–specific feed could be the keys to achieving strong productivity and delivering product to market more rapidly.

  6. Clinical Supply Optimization: Process Improvement Accelerates Clinical Trial Deliverables And Execution 6/3/2022

    A biopharmaceutical sponsor required the study startup phase to be reduced to 91 days, involving comparator sourcing and blinding, kitting, packaging, labelling and distribution to the sites.

  7. Pilot And Manufacturing Scale Comparison Of DynaDrive SUB Capabilities 6/1/2022

    We demonstrate that how processes can be successfully transferred across different systems without impacting the process performance or product quality.

  8. Engineering Approaches To Respiratory Drug Delivery: Mannitol Case Study 5/27/2022

    This article presents a case study that explores the material and performance properties of spray-dried and jet-milled mannitol for respiratory delivery of crystalline mannitol.

  9. How Service Providers Can Create Momentum In An Established Brand 5/27/2022

    To promote brand growth, companies must identify which brand components are succeeding and which may be falling short, as well as understand how these dynamics manifest in the larger organization’s successes and failures.

  10. Catalent Cell And Gene Therapy Utilizes Robotic Aseptic Filling Systems To Meet Industry Needs 5/19/2022

    An aseptic filling and closing machine solution allowed Catalent to reliably process a wide range of both trayed and nested vials for their client product needs.