Application Notes & Case Studies

1. Recommended Mixing Technologies for Producing Capsule Shells 4/23/2021

   Capsule shell chemistries today must meet a myriad of requirements, including those affected by consumer preferences, the need for compatibility with active pharmaceutical ingredients, a formulation's dissolution rates and moisture sensitivity, the acceptable oxygen permeability, and the overall product stability. Given the different raw materials and application requirements at play, you can simplify mixer selection for a particular capsule-shell formulation by considering the formulation's viscosity and the appropriate level of shear.

2. Microbial Air Sampling For Pharma - Physical And Biological Collection Efficiencies 4/23/2021

   Even though impaction-based microbial samplers have been in use since the middle of the 20th century, currently there is no standard defining minimum performance requirements. As a result, there are significant differences in performance for AASs in use today, which can lead to improper evaluation of cleanroom microbial contamination levels. Therefore, proper characterization of microbial air sampler performance is a critical aspect of a contamination control program.

3. Meta Biomed Accelerates Digital Transformation 4/23/2021

   Meta Biomed's scientists ran hundreds of experiments, but they lacked a clearly defined way of sharing information and knowledge between individuals and teams. They also wanted to centralize their product development data and achieve a more structured way of working to boost innovation, embed quality throughout the supply chain and accelerate product certifications—especially as they sought to become a leading supplier of surgical sutures in the global market. A single, centralized database solution now allows them to hold all of their product development data.

4. Leading Biotech Upgrades Its Freezer Inventory System 4/23/2021

   A leading biotechnology company's existing CISPro system did not include freezer inventory management for use by their process development team. By implementing the BIOVIA CISPro they can manage all the chemicals and materials across their facilities at the container level, keep track of where they are in real-time and monitor usage.

5. Streamlined, Scalable And Secure Research Collaboration 4/22/2021

   A global healthcare leader in discovery, development and distribution of therapeutics had an in-house systems that was outdated and not easily adapted for the new types of data emerging from the shift toward biologics and novel bioactivity data. Their solution was an open ecosystem of cloud-based, web-accessible research applications provided a secure project management framework with the ability to share project information (whether structured data or documents) using a unique social networking approach.

6. Integrated Lab Operations For Efficiency And Compliance 4/21/2021

   a research-based biopharmaceutical company had recently transitioned from paper-based experimental documentation towards increasingly electronic-based systems. However disconnected digital lab informatics systems with inefficient lab processes and compliance risks resulting from poor integration and paper-based workflows. Through the integration of their lab informatics systems the customer has observed improvements in both compliance and workflow efficiency.

7. Spray-Dried Dispersions Enable Local Delivery For Lung Cancer 4/20/2021

   Spray drying is a useful particle engineering technique that can deliver the particles within the necessary specifications and can therefore be used to manufacture dry powder inhaler treatments. Learn more about spray drying, and discover two case studies detailing its success.

8. Drug R&D Services Leader Implements A Collaborative Enterprise ELN To Advance Research 4/20/2021

   In a demanding and increasingly distributed research environment, drug discovery alliance companies can only attract and maintain collaborations by being responsive and providing high quality results as quickly as possible. What mattered to this BIOVIA customer in meeting collaboration demands, however, was being able to rapidly collect together project information to deliver reports and data, fulfill patent submissions, or leverage and build on past work.

9. Cloud-Based ELN Streamlines Med Device Development 4/20/2021

   A leading medical device and in vitro diagnostics technology company's research & development scientists were using traditional paper notebooks to record all of their procedures, experimental results, and testing methods. They turned to BIOVIA Notebook— a flexible electronic lab notebook (ELN) hosted on BIOVIA ScienceCloud, a scalable cloud infrastructure. With BIOVIA Notebook, the customer was able to quickly replace paper-based processes across their R&D labs, speeding up workflows and improving data accuracy.

10. Accelerating Results For Healthcare Brands Through Advocacy, Materials Science Expertise And Integrated Packaging Capabilities 4/15/2021

    Any change to packaging design for an approved pharmaceutical product is a time consuming, detail-orientated effort, even with small brand-driven changes––so when governments update packaging regulations on a larger scale, a company’s entire product line could be impacted, creating change management projects for sometimes hundreds of items. When Health Canada introduced amendments to the existing Food and Drug Regulations for non-prescription, over-the-counter (OTC) drug products in 2014, pharmaceutical organizations selling products in the Canadian marketplace knew they had a significant challenge to overcome