Application Notes & Case Studies

  1. Predicting Food Effects In Oral Drug Delivery Using PBPK Modeling 7/15/2026

    Learn how integrated PBPK and molecular dynamics modeling predicted an ~11% fed-state Cmax increase for fenofibrate, giving formulation teams earlier, mechanistic insight into food-dependent absorption.

  2. Compaction Simulation For Tablet Technology Transfer And Scale-Up 7/15/2026

    Compaction simulation de-risked tech transfer for a 40 mg fexuprazan tablet by defining optimal roller compaction and lubrication parameters before scale-up. Access the full case study to see the data.

  3. Predicting Softgel Stability And Shelf Life Using Accelerated Modeling 7/15/2026

    Predict ibuprofen softgel shelf life in 21 days instead of years. ASAPprime modeling identified PEG-ester degradants as the limiting factor, estimating 5.5-year and 3.8-year shelf lives before long-term studies concluded.

  4. Predicting Drug-Loading Limits In Tablet Formulations 7/15/2026

    Learn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.

  5. Modeling Polymer Interactions To Improve Amorphous Solid Dispersion Stability 7/15/2026

    Molecular dynamics modeling revealed how hydrogen bonding between PVP and Eudragit drives stable amorphous solid dispersion formation, cutting formulation screening time significantly.

  6. Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement Strategies 7/15/2026

    In silico modeling cut through formulation guesswork for a compound with 0.015 mg/mL solubility, delivering an 8× Cmax and 5× AUC improvement and Phase I progression.

  7. Unlocking Robust Separations For Modern Peptide Therapeutics 7/14/2026

    As peptide therapeutics grow more complex, impurity profiling demands greater chromatographic confidence. See how robust reproducibility can support reliable GLP-1 receptor agonist analysis.

  8. Using dSEC-7 Column For Separation And Length Determination Of mRNA 7/13/2026

    mRNA analysis depends on methods that can separate broad size ranges. Learn how retention time can help estimate transcript length and complement capillary electrophoresis workflows.

  9. What Is Size Exclusion Chromatography (SEC)? 7/13/2026

    Aggregation can compromise mAb quality at many stages of development. Learn why size exclusion chromatography is a trusted approach for detecting aggregates and supporting confident characterization.

  10. Peptide Mapping Of Adeno Associated Virus Capsid Proteins 7/13/2026

    Peptide mapping helps reveal AAV capsid protein identity, sequence coverage, and potential modification patterns, giving gene therapy teams a clearer view of viral protein quality across workflows.