Application Notes & Case Studies

  1. Cryobag Container Development For Cell & Gene Therapies 12/8/2022

    The logistical challenges developers of cell and gene therapies face regarding cold chain and cryopreservation are daunting. A biopreservation company contacted ISR Reports to gain insight into these challenges, understand the level of concern about losing CAR-TCR product due to breakage or contamination, and to assess the markets’ interest level and need for a Cryobag Container product.

  2. A Versatile Method For Capsule And Depth Filtration 12/7/2022

    Learn about a solution that can provide a simple, easy, and versatile method for capsule and depth filtration, allowing a quick, efficient move from cell harvest to purification.

  3. How To Save 9k Hours And Cut Deviations By 27% 12/2/2022

    This pharma company transitioned off paper, slashing their deviation count and saving thousands in onsite hours. Learn how they were able to streamline business operations and free up resources.

  4. Helium Leak Detection And Vial Crimp Force Measurements 12/1/2022

    A global pharmaceutical equipment entity was interested to see how various levels of crimping force in vials affect helium leak rate data. Explore the results obtained from this case.

  5. Delivering Pre-IND To IND Safety Studies In Just Three Months 11/29/2022

    A biotech company partnered with an integrated research, development and manufacturing services company to deliver pre-IND to IND safety studies for a treatment therapy for gut-brain diseases.

  6. Cold And Ultra Cold Vial Helium Leak Testing 11/22/2022

    A global pharmaceutical entity was comparing vials for helium leak testing services. Learn about the results obtained from collecting and tabulating helium leak rate data along with the solution.

  7. Helium Leak Detection Vs. Dye Leak Testing 11/22/2022

    A global pharmaceutical entity was experiencing early package failures from stability studies for a new drug product. Learn about the solution and the results obtained from this case.

  8. SELECT SERIES Cyclic IMS System 11/17/2022

    Explore the utility of Electron Capture Dissociation (ECD) on the SELECT SERIES Cyclic IMS instrument for unambiguous assignment of glycosylation site locations for 11 Oglycopeptide species of ENBREL (etanercept).

  9. Capture Of Bispecific Antibodies And Removal Of Product-Related Impurities 11/17/2022

    Many antibody variants are prone to aggregation or to forming product-related impurities. Explore the application of a resin with novel selectivity to purify challenging entities.

  10. Evaluating A Flexible LC Platform 11/16/2022

    Learn about a premier system offering a flexible LC platform that can be broadly deployed across labs to support the analytical needs in the development and manufacturing of biotherapeutics.