Application Notes & Case Studies

  1. Improving API Solubility With Mesoporous Silica 6/5/2025

    Poor solubility of active pharmaceutical ingredients can hinder drug effectiveness. Learn how innovative formulation strategies enhance solubility and bioavailability to improve therapeutic outcomes for challenging drug candidates.

  2. Improving API Solubility Using Spray Drying With Polyvinyl Alcohol 6/5/2025

    Enhancing the solubility of poorly soluble APIs is vital for improving bioavailability and therapeutic outcomes. Discover how advanced formulation techniques like hot-melt extrusion and spray drying can overcome this challenge.

  3. API Solubility And Dissolution Enhancement Via Formulation 6/4/2025

    Solubility and dissolution rate of an API are essential for effective oral drug absorption. Discover how these factors directly influence bioavailability, which determines how much and how quickly a drug enters circulation.

  4. Benchmarking Filtration Performance Of TFF Cassettes 5/30/2025

    Optimize your protein purification workflow with tangential flow filtration by comparing membrane performance and exploring how protein concentration impacts flux and MWCO selection in lab-scale systems.

  5. Flow Chemistry Experiments Of Highly Hazardous Butyl Lithium Reactions 5/22/2025

    By adopting flow chemistry for a production platform that reduces utility costs and solvent consumption, researchers can overcome the risks and challenges of Butyl Lithium chemistry.

  6. Robust, Scalable Strategy For Monodisperse Nanosuspensions Of Poorly Soluble Drugs 5/16/2025

    By tailoring the formulation strategy, selecting the appropriate excipients, and fine-tuning process conditions, see how our team was able to improve bioavailability and in vivo exposure.

  7. Modelling TPDs Utilizing Computational And Medicinal Chemistry Approaches 5/16/2025

    Through a carefully executed strategy, see how we identified novel degrader molecules with the right physicochemical properties to achieve robust degradation of the target Protein of Interest (POI).

  8. Bend Successfully Rescues Powder-Filled Capsule Program 5/16/2025

    Learn how to overcome tech transfer challenges and ensure consistent content uniformity by leveraging multidisciplinary expertise and decades of commercial encapsulation experience.

  9. Enabling Transfer Of Raman Calibration Models Across Bioreactor Scales 5/16/2025

    Raman spectroscopy has revolutionized manufacturing through real-time monitoring. Explore a system that enables a seamless calibration model transfer from small- to large-scale bioreactors to enhance scalability and efficiency.

  10. Top 10 Pharma Company Uses Validation Technology To Streamline CQV 5/14/2025

    Discover how a Top 10 global pharma company saved over $900K using validation technology, as well as explore their digital CQV transformation to learn how you can achieve similar results.