Application Notes & Case Studies

  1. Digitalizing Batch Records In Pharmaceutical Production 6/13/2025

    Pharma manufacturing embraces cutting-edge automation, yet outdated paper-based documentation hinders efficiency and delays batch releases. Discover how digital solutions can transform compliance and innovation.

  2. Digital Twins: A Game-Changer Throughout The Pharmaceutical Lifecycle 6/13/2025

    Discover how end-to-end digital twins and Integrated Process Models are transforming pharmaceutical manufacturing to enhance flexibility, accelerate time-to-market, and enable real-time decision-making through MES integration.

  3. Real-Time Monitoring Of Solvent Clearance By TFF In The ADC Process 6/13/2025

    Raman spectroscopy revolutionizes ADC manufacturing by enabling real-time monitoring of solvent clearance. Discover how it enhances process control, ensures regulatory compliance, and supports the production of high-quality therapeutics.

  4. Jaw Crimping vs. Rotary Crimping: Enhancing Aseptic Assurance 6/12/2025

    Beyond a simple mechanical step, crimping is a critical control point. We examine how advanced rotary technology provides superior seal quality, particulate control, and data-driven compliance assurance.

  5. Site Transfer Of Tablet Production From Ex-U.S. To Georgia Site 6/11/2025

    Explore how strategic U.S.-based manufacturing and supply chain diversification can reduce risk, lower costs, and enhance supply reliability for pharmaceutical products.

  6. Modifying The Micro-Environment To Improve Dissolution Rate 6/11/2025

    Discover how modifying the micro-environment with targeted excipients can significantly enhance the dissolution rate of poorly soluble drugs using conventional manufacturing methods.

  7. Comparing Serum-free To Serum-Supplemented Media 6/9/2025

    Reducing serum in vaccine manufacturing is a key consideration for lowering costs and improving supply security. We compare performance in serum-free versus serum-supplemented media.

  8. A Temperature-Stable Replacement For Animal Trypsin In Cell Dissociation Applications 6/9/2025

    Improve cell dissociation with a gentle, recombinant enzyme. This temperature-stable protease shows dissociation kinetics similar to porcine trypsin but with lower cell toxicity and greater overall purity.

  9. Improving API Solubility With Mesoporous Silica 6/5/2025

    Poor solubility of active pharmaceutical ingredients can hinder drug effectiveness. Learn how innovative formulation strategies enhance solubility and bioavailability to improve therapeutic outcomes for challenging drug candidates.

  10. Improving API Solubility Using Spray Drying With Polyvinyl Alcohol 6/5/2025

    Enhancing the solubility of poorly soluble APIs is vital for improving bioavailability and therapeutic outcomes. Discover how advanced formulation techniques like hot-melt extrusion and spray drying can overcome this challenge.