Application Notes & Case Studies

1. Why Early Device Decisions Matter: How Immunovant Accelerated Its Program 10/15/2026

   Deferring autoinjector selection can seem to preserve flexibility, yet it often moves constraints downstream. Integrating the device during Phase IIb changed one program's timeline and removed bridging work.

2. Using Human-Centered Engineering To Improve HPLC Solvent Handling 10/15/2026

   Real-world HPLC workflows show how closed-system solvent handling can address contamination, downtime, and waste across laboratory settings.

3. Supply Chain Diversification In Biopharmaceutical Manufacturing 10/15/2026

   Single-source dependencies in biologics manufacturing carry risks that surface as programs scale toward commercial production. 

4. Reducing Cycle Time By 88% Through Strategic Solvent Replacement In Pharmaceutical Development 10/14/2026

   Replacing methylene chloride in a slow, labor-intensive API step led to a single-solvent, one-pot process with a shorter reaction time and improved yield and purity.

5. The Effects Of Tubing Length On Airborne Particulate Sampling 10/14/2026

   Tubing between sampling point and counter quietly shapes what gets measured. Half-micron counts barely flinch, but five-micron particles tell a very different story.

6. Adherent PSC Expansion: Key Considerations For Scalable Manufacturing 10/13/2026

   Adherent multilayer vessels let PSC cultures scale without changing familiar media and handling, but coating volumes, seeding density, and harvest recovery all need rethinking.

7. Improving Stability Through Science-Led OSD Reformulation 10/13/2026

   A marketed multivitamin tablet spanning a 0.03% to 46% w/w range failed early in accelerated stability testing. Mechanism-led reformulation and a switch to direct compression changed the outcome.

8. De-Risking Complex Generic OSD Development 10/13/2026

   Complex generic tablet development requires early alignment of regulatory strategy, QbD formulation, discriminatory dissolution, and reference-scaled bioequivalence.

9. Crude Peptide Purification Optimization For Scalable Manufacturing 10/7/2026

   Transitioning lentiviral vectors to final drug product raises quality demands. A simplified membrane-based capture step minimizes downstream losses that can constrain systemic dosing.

10. Reduce Complexity, Not Quality In CAR T Cell Manufacturing 9/29/2026

    Fragmented CAR T cell manufacturing workflows drive up costs and extend timelines. This case study quantifies what consolidating manufacturing and QC through automation actually delivers.