Application Notes & Case Studies

1. Characterizing Binding Interactions By ITC 4/24/2025

   Isothermal Titration Calorimetry is a powerful technique for analyzing biochemical binding events, which is crucial for understanding molecular interactions and enzyme kinetics in biomedical research.

2. A Novel Patient-Derived Colorectal Cancer Organoid Platform 4/22/2025

   Patient-derived organoids are revolutionizing drug discovery by mimicking tumors and predicting therapeutic efficacy. Discover a scalable bioprocess that enhances reproducibility and cost-effectiveness to pave the way for broader adoption.

3. Transfer Of Fed-Batch To Semi-Perfusion Process 4/14/2025

   Continuous processes enhance product quality, yield, and cost savings. Explore transitioning a fed-batch process to perfusion using a small batch bioreactor system to optimize cell culture conditions and comparing performances.

4. Improve Productivity And Reduce Risk With Biostat® RM 4/14/2025

   Discover how a company overcame cell generation challenges by using a system that achieves a seed ratio of 1:120 and saves four days in seed preparation time.

5. Navigating Regulatory Compliance: A Success Story In The Pharma Industry 4/10/2025

   See how one pharmaceutical facility overcame strict cross-contamination rules and space limits without costly building modifications, ensuring operational continuity.

6. Optimizing TFF And SPTFF For High-Concentration mAb Formulations 4/9/2025

   Discover the critical role of formulation buffer composition in stabilizing monoclonal antibodies during tangential flow filtration, a process involving ultrafiltration and diafiltration under high pressure and shear forces.

7. Selecting A Platform Filter For High Concentration mAbs 4/9/2025

   Read more about how Fujifilm Diosynth Biotechnologies evaluated a prime filter with challenging simulant solutions and how the experimental data confirmed superior performance, which demonstrated twice the throughput.

8. A Study To Assess Organoid Size And Cell Count From 3D Image Analysis 4/4/2025

   Recent advancements in 3D patient-derived organoids (PDOs) offer improved predictive power over traditional 2D assays. Explore a patented bioprocess for PDO expansion that could revolutionize drug discovery, especially in oncology.

9. Sensitive RNA Fluorescent Quantitation With An RNA Assay Kit 4/4/2025

   Accurate nucleic acid quantification is vital for applications like PCR and NGS. Discover an RNA Assay Kit that offers precise RNA measurement to enhance reliability and performance in downstream assays.

10. Rapidly Assess Drug Response In 2D And 3D Breast Cancer Model Systems 4/4/2025

    For years, 2D cell cultures have been crucial in drug discovery. Explore how 3D cultures offer more biologically relevant models today that enhance cancer research and drug efficacy assessments.