Application Notes & Case Studies

1. Successful Site Transfer Of Tablet Production From Ex-US To Georgia Site 6/11/2025

   Learn how strategic U.S.-based manufacturing and supply chain diversification can reduce risk, lower costs, and enhance supply reliability for pharmaceutical products.

2. Modifying The Micro-Environment To Improve Dissolution Rate 6/11/2025

   <p>Discover how modifying the micro-environment with targeted excipients can significantly enhance the dissolution rate of poorly soluble drugs using conventional manufacturing methods.</p>

3. Comparing Serum-free To Serum-Supplemented Media 6/9/2025

   Reducing serum in vaccine manufacturing is a key consideration for lowering costs and improving supply security. We compare performance in serum-free versus serum-supplemented media.

4. A Temperature-Stable Replacement For Animal Trypsin In Cell Dissociation Applications 6/9/2025

   Improve cell dissociation with a gentle, recombinant enzyme. This temperature-stable protease shows dissociation kinetics similar to porcine trypsin but with lower cell toxicity and greater overall purity.

5. Improving API Solubility With Mesoporous Silica 6/5/2025

   Poor solubility of active pharmaceutical ingredients can hinder drug effectiveness. Learn how innovative formulation strategies enhance solubility and bioavailability to improve therapeutic outcomes for challenging drug candidates.

6. Improving API Solubility Using Spray Drying With Polyvinyl Alcohol 6/5/2025

   Enhancing the solubility of poorly soluble APIs is vital for improving bioavailability and therapeutic outcomes. Discover how advanced formulation techniques like hot-melt extrusion and spray drying can overcome this challenge.

7. API Solubility And Dissolution Enhancement Via Formulation 6/4/2025

   Solubility and dissolution rate of an API are essential for effective oral drug absorption. Discover how these factors directly influence bioavailability, which determines how much and how quickly a drug enters circulation.

8. Benchmarking Filtration Performance Of TFF Cassettes 5/30/2025

   Optimize your protein purification workflow with tangential flow filtration by comparing membrane performance and exploring how protein concentration impacts flux and MWCO selection in lab-scale systems.

9. Flow Chemistry Experiments Of Highly Hazardous Butyl Lithium Reactions 5/22/2025

   By adopting flow chemistry for a production platform that reduces utility costs and solvent consumption, researchers can overcome the risks and challenges of Butyl Lithium chemistry.

10. Robust, Scalable Strategy For Monodisperse Nanosuspensions Of Poorly Soluble Drugs 5/16/2025

    By tailoring the formulation strategy, selecting the appropriate excipients, and fine-tuning process conditions, see how our team was able to improve bioavailability and in vivo exposure.