Containment & Isolation Feature Articles

  1. Sterile Drug Manufacturing Techniques: Key Benefits To Know

    Although pharmaceutical manufacturers take stringent steps to ensure that their production systems are as safe as possible, a fully gowned operator can still create as many 150,000 particles per minute, meaning that drug manufacturing is never a completely hazard-free process.

  2. Biocontainment Strategies: Defining The Boundaries

    Successful biocontainment strategies are holistic, with a focus on defining boundaries, training, careful logistics and consistent implementation.

  3. Reducing Bioburden Risks In Aseptic Manufacturing

    Manufacturers can benefit from this alternative transfer technology that has now been adapted to solve issues in aseptic handling.

  4. How To Prepare For Chamber Mapping In Life Sciences — 8 Critical Steps

    A failed chamber mapping study can lead to unnecessary costs in valuable biopharmaceutical production time or regulatory and product quality issues.

  5. Aseptic Production Automation To Reduce Risk And Cost

    This article discusses how to apply current isolation technologies with robotic systems to reduce the risk of microbial contamination in aseptic processes caused by human intervention.

  6. Increase In HPAPI Manufacturing Highlights Need For Containment And Isolation Systems

    An estimated 25 percent of globally manufactured drugs contain highly potent active pharmaceutical ingredients (HPAPIs). HPAPI drugs, which include small-molecule and biologic compounds as well as antibodydrug conjugates (ADCs), are often used in the treatment of cancer. The fastest growing segment of the HPAPI market are ADCs, a new class of therapeutic agents that deliver cytotoxic drugs selectively to antigen-expressing tumor cells. Non-oncology HPAPI compounds include hormones, narcotics, and retinoids.

  7. FAQ's: Regulated Films For Containment Solutions

    At ILC Dover, we are always "creating what’s next" by listening carefully to our customers. In response to customer input and emerging regulations, we've developed a robust new film to support our DoverPac® Containment Solutions line. This revolutionary product, ArmorFlex® 110, delivers permanent static dissipative properties while meeting FDA and 2002/72/EC requirements for food contact.

  8. ILC Dover Verifies That DoverPac™ Flexible Containment Systems Are Compliant With REACH
    As the leader in flexible containment and disposable cGMP systems, ILC Dover, with the assistance of an independent third party consultant, has reviewed the products they offer to the pharmaceutical industry with regard to the REACH regulation.
  9. Article: Test Area Validation And Flexible Containment System Performance: Testing To The SMEPAC 2005 Guidelines

    Article: Test Area Validation And Flexible Containment System Performance: Testing To The SMEPAC 2005 Guidelines

  10. A Novel Design To Contained Transfer Of Drummed Materials Using A Disposable Manufacturing Approach

    The Drum Transfer System (DTS) described in this article has been validated in a variety of processes requiring the contained transfer of drummed materials in pharmaceutical applications. Processing operations described here include milling, subdividing, charging, and repackaging. Submitted by ILC Dover