Insights On Outsourced Drug Development
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A Tale Of Two Brothers: The Abpro Founders
12/11/2023
By founding their latest venture, Abpro, Ian and Eugene Chan are using their synergistic skillsets in business and medicine to rapidly generate antibodies that treat cancer and autoimmune diseases.
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Host Cell Impurities, Bioassays, Micro-Flow Imaging
4/9/2024
Ensuring the safety and efficacy of cutting-edge biopharmaceuticals hinges on meticulous quality control measures. Explore the role of qPCR and MFI in safeguarding drugs from potential contamination.
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Method Development of Ten Antibiotic Compounds Using A Systematic Screening Protocol
9/21/2022
Effective method development of LC and LCMS methods typically involve highly experienced scientists with a wealth of knowledge that has been handed down throughout their organization. For some particularly challenging and complex mixtures this experience may not be enough. Learn how Waters leveraged a generic systematic protocol to separate a variety of APIs in a single run.
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Powerfully Simple Digital PCR
7/18/2023
Evaluate the performance of an E. coli kit based on it's detection sensitivity, quantification accuracy, and replicate uniformity as it performed when tested on a Digital PCR System.
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A More Human-Relevant Model To Advance AAV-Based Gene Therapies
3/8/2024
Learn about a liver-chip that offers a more human-relevant way of testing viral vectors compared to conventional models and why it is a promising tool for advancing AAV gene therapy.
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The Flux Performance Of Nanoformed And Untreated PRX Solid Suspensions
7/26/2023
Explore the application of in vitro flux assays to nanoparticles, with data on how the in vitro permeability apparatus can characterize the membrane flux performance of an API formulated as a nanosuspension.
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Cytokine-Mediated Inflammation In A Relevant Preclinical Model
3/13/2024
Learn about a novel preclinical model and how it enables the study of cytokine-mediated barrier inflammation mechanisms as well as the efficacy of anti-inflammatory therapeutics.
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Overcoming The Challenges Of Cell Therapy Manufacturing
10/17/2022
Learn more about how allogeneic approaches have the power to revolutionize the use of CAR T-cell therapies.
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Validated LC–MS/MS Method For The Determination Of Copanlisib
11/14/2022
Review study findings on a validated LC–MS/MS method for quantifying copanlisib from a mouse dried blood spot and its potential for enabling desirable sensitivity, accuracy, and precision.
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Predictive Validity: The Key To Improving The Drug Development Process
2/13/2024
The drug development industry recognizes the importance of predictive validity, but Jack Scannell, the author of Eroom’s law, and a team of experts argue it is far more crucial than most believe it is.