Insights On Outsourced Drug Development

  1. The Flux Performance Of Nanoformed And Untreated PRX Solid Suspensions 7/26/2023

    Explore the application of in vitro flux assays to nanoparticles, with data on how the in vitro permeability apparatus can characterize the membrane flux performance of an API formulated as a nanosuspension.

  2. Reproducibility Study Of A High-Throughput Released N-Glycan Workflow 8/9/2023

    This fast glycan labeling and analysis kit demonstrated that it could yield 576 data points from 2 instruments, 2 cartridges and 3 chemistry kits during inter- and intracapillary reproducibility validation.

  3. Beyond SOPs: Assessing Quality Of CDMOs 5/16/2024

    When choosing a CDMO partner, it is essential to prioritize quality. Discover how the right partner can instill confidence in the safety and effectiveness of your pharmaceutical products.

  4. Manual Whole-Cell Patch Clamp Assay For Screening NCE's Against Voltage Gated Ion-Channels 5/13/2025

    Ensure the cardiac safety of your drug candidates by leveraging manual whole-cell patch-clamping to assess their impact on hERG channel interactions and prevent potential QT prolongation risks.

  5. Preclinical Immuno-Oncology Models For CAR T-Cell Therapy Development 5/21/2025

    The following preclinical IND-enabling oncology studies conducted by scientists at Aragen over the past 10 years highlight the role of robust preclinical models in advancing the fight against cancer.

  6. Preclinical Model Of Post- Incisional Pain For Efficacy Testing Of Novel Therapeutics 5/16/2025

    Explore how validated preclinical models of incision-induced pain can accelerate the development of effective therapies for postoperative pain by closely mimicking human pain responses.

  7. Accelerate Your R&D And QC With These 3 Key Analysis Methods 5/4/2024

    Learn about three key thermal analysis methods for fast and effective characterization and quality control: differential scanning calorimetry, thermogravimetric analysis, and sorption analysis.

  8. High-Throughput IgG Quantification Assay For Cell Line Development 4/4/2025

    Monoclonal antibodies are revolutionizing treatment for various diseases, which include cancer and autoimmune disorders. Discover how improving production methods can reduce costs and enhance accessibility.

  9. Overcoming Challenges To High-Concentration Formulation Development 3/25/2025

    Explore how the S-HiCon™ platform optimizes high-concentration therapeutic antibody formulations, overcoming stability and manufacturability challenges to deliver safe, effective therapies.

  10. An Alternative Method Of Drug-Excipient Characterization 12/30/2024

    Isothermal microcalorimetry (IMC) rapidly screens API-excipient compatibility, detecting physical and chemical interactions faster than conventional methods, saving time and effort in pharmaceutical formulation development.