Insights On Outsourced Drug Development

  1. Validating Antibodies With Knock-Out Technologies 10/8/2024

    Watch to learn about how one company achieves antibody validation through knock-out (KO) technologies as well as the significance of gene KO technologies in the large-scale screening of antibodies.

  2. Improving API Solubility Using Spray Drying With Polyvinyl Alcohol 6/5/2025

    Enhancing the solubility of poorly soluble APIs is vital for improving bioavailability. Discover how advanced formulation techniques like hot-melt extrusion and spray drying can overcome this challenge.

  3. Experimental λ-Carrageenan-Induced Inflammatory Pain Model For Testing Novel Analgesics 5/13/2025

    Explore reliable and reproducible λ-Carrageenan-induced inflammatory pain models for effective preclinical screening of promising analgesic candidates targeting chronic pain.

  4. Addressing Raw Material Handling Challenges By Dry Granulation 8/12/2025

    Handling multi-ton quantities of buffers, salts, and stabilizing chemicals in manufacturing can be difficult. Discover how dry granulation improves efficiency, safety, and process reliability.

  5. Overcoming The Solubility Challenges Of Antibody-Drug Conjugates 6/3/2024

    Discover a chito-oligosaccharide that significantly improves the solubility of antibody-drug conjugates (ADCs) when included in the linker-payload construct.

  6. Multiplex Imaging 3/24/2025

    Explore recombinant antibody reagents that support the imaging of key targets within the TME and offer flexible solutions across various platforms to improve patient outcomes.

  7. Unleash The Potential For Polyvinyl Alcohol In Spray Drying 6/4/2025

    Discover how polyvinyl alcohol (PVA) addresses key formulation challenges in oral solid dosage forms to enhance solubility and stability across diverse APIs, which include emerging drug classes like PROTACs.

  8. Flow Chemistry Experiments Of Highly Hazardous Butyl Lithium Reactions 5/22/2025

    By adopting flow chemistry for a production platform that reduces utility costs and solvent consumption, researchers can overcome the risks and challenges of Butyl Lithium chemistry.

  9. Advantages Of Spray-Dried Mannitol In Roll Compaction 4/2/2025

    Pharmaceutical excipients like mannitol enhance formulation stability, flowability, and compressibility, which are crucial for robust tablets. Read how these properties improve patient compliance.

  10. Target Product Profiles And Phase 1 Clinical Plans: Laying The Groundwork For Success 2/26/2025

    By integrating scientific rigor, regulatory foresight, and market awareness into early-stage planning, companies can leverage a robust TPP to optimize decision-making and development.