Insights On Outsourced Drug Development

  1. Beyond SOPs: Assessing Quality Of CDMOs 5/16/2024

    When choosing a CDMO partner, it is essential to prioritize quality. Discover how the right partner can instill confidence in the safety and effectiveness of your pharmaceutical products.

  2. A New Framework For Identifying Nitrosamine Risks And Derisking Products 6/18/2024

    Examine a new methodology that holds significant promise for identifying APIs at risk for NDSRI formation, enabling manufacturers to prioritize risk mitigation strategies and ensure compliance.

  3. Innovative Octet® Biolayer Interferometry (BLI) Approach For Non-Disruptive And Fast AAV Capsid Ratio Determination In Complex Biological Matrices 9/27/2024

    Learn about a biosensor that was designed to provide the rapid, real-time, high-throughput measurement of AAV capsid titer in samples throughout the AAV workflow.

  4. Finding The Right Formulation… Faster And More Efficiently 1/4/2024

    Finding the right formulation for a new product is a challenging part of research and development. Learn about powder rheology, an effective tool for accelerating formulation and development in pharma.

  5. AAV Full/Empty Capsid Separation Using Mechanistic Modeling 5/1/2023

    In this study, we used mechanistic modeling to investigate how AAV-resin interactions are affected when MgCl2 is used as an elution additive.

  6. Monolithic Columns As Downstream Processing Solutions For Lentiviral Purification 11/27/2024

    Third-generation lentiviral vectors enable efficient gene delivery, but purification challenges limit in vivo applications. Monolithic columns and advanced assays show promise for downstream processes.

  7. Assessment Of Compound Toxicity Effects With High-Content Imaging 3/17/2025

    3D cellular models and bioprinting enhance drug safety predictions and offer precise spatial control. Explore an automated method for generating liver models to improve reproducibility and reliability in toxicity testing.

  8. 2D To 3D Transition Of Mesenchymal Stem Cell Expansion Process 4/4/2025

    Discover how transitioning from 2D to 3D culture methods enhances the scalability, yield, and quality of Mesenchymal Stem Cells (MSCs) for therapeutic applications to address critical manufacturing challenges.

  9. Welcoming The "Era Of ADCs" 12/5/2023

    Dr. Loretta Itri sat down to explore the promise of TRODELVY®️ and other antibody-drug conjugates as transformative treatments for a range of malignancies and intractable diseases.

  10. What Is A Viral Vector? 4/16/2024

    Review a novel adenovirus production process that offers scalable, single-use equipment-compatible solutions, reducing production time and cross-contamination risks.